DEACETYLASES相关论文
Pancreatic cancer,although not very frequent,has an exceptionally high mortality rate,making it one of the most common c......
Pancreatic cancer is one of the most aggressive human cancers,with more than 200 000 deaths worldwide every year.Despite......
Cardiovascular diseases (CVDs), which include alldiseases of the heart and circulation system, arethe leading cause of dea......
The increasing incidence of obesity worldwide and its related cardiometabolic complications is an urgent public health p......
DFT Study, Linear and Nonlinear Multiple Regression in the Prediction of HDAC7 Inhibitory Activities
In this work, we conducted a QSAR study on 18 molecules using descriptors from the Density Functional Theory (DFT) in or......
Sirtuins(SIRTs)are NAD+-dependent histone deacetylases and play a role in virtually all cell biological processes.As SIR......
Because pancreatic cancer(PC)historically has had poor prognosis and five year survival rates,it has been intensely inve......
QSAR Studies on the Inhibitory Activityof Levofloxacin-thiadiazole HDACi Conjugates to Histone Deace
A molecular electronegativity distance vector(Mt)based on 13 atomic types has been used to describe the structures of 19......
Valproic Acid, a Drug with Multiple Molecular Targets Related to Its Potential Neuroprotective Actio
Valproic acid (VA) is used worldwide as an antiepileptic drug and a mood stabilizer. Recently, VA was shown to act on ce......
Putative and known polysaccharide deacetylases (PDAs) from B. anthracis have key roles in resistance to host lysozyme, s......