Infectious caused by intracellular pathogens,such as viral,bacterial and parasites have been a serious worldwide public ......

Photodynamic therapy(PDT)has emerged over the past decades as a very active field of research for medical applications.P......

Aim: To determine the effect of selected medicinal plants on Mycobacterium tuberculosis cultured under anaerobic conditi......

Objectives:To reveal the mechanisms behind the dual effects of Crataegus aronia(C.aronia)aqueous extract on platelet agg......

The phenomena of saltatory movements of intracellular particles (including organelles) in living cells have been repeate......

In this paper,the relationship of intracellular acidification and apoptosis in Hela cells induced by vin-cristine sulfat......

The release of intracellular water during degradation process contributes to the great leachate production and settlemen......

This study measured platelet intracellular free calcium (PFCa 2+ ) of 1003 normal pregnancies in different trimester......

The chemical structure of end groups influenced the phase transition temperature of thermoresponsive polymers. We demons......

Objective To investigate the effects of rapamycin on cholesterol homeostasis of glomerular mesangial cells and the under......

Objective To observe effects of Chaihu Shugan Powder(CSP)on the cytoactivity and intracellular Ca~(2+)concentration of r......

AIM To determine whether Nucb2/nesfatin1 production is regulated by the cannabinoid system through the intracellular m T......

A simple,water-soluble,Fe~(3+)-selective fluorescent probe,derived from rhodamine B,was synthesized and characterized.Th......

Two new iridium complexes,(dfppy)_2Ir(L-alanine)(dfppy = 2-(2,4-difluorophenyl)pyridine) and(piq)_2Ir(L-alanine)(piq = 1......

Oxidative stress stimulated by angiotensin II(Ang II) plays an important role in the progression of inflammation and car......

Re(I)tricarbonyl rhenium(I)complexes attracted much attention owing to the good cellular uptake ability and rich photoph......

Objective To explore the effect of the interaction between microphage colony-stimulating factor(M-CSF)and minichromosome......

Chemosensors and imaging probes have been the focus of significant research interest over the past few decades.In part d......

Human β-definsin-2(hBD-2)is mainly induced by bacterial factors and pro-inflammation mediators in epithelial cells.As t......

Background Advanced glycation end products (AGEs) play a critical role in the development of diabeticnephropathy.Reacti......

AIM: To determine the possible role of pH in mediating activation of p38 mitogen-activated protein kinase (MAPK) and the......

Objective: To study the effect of KATp channel opener and its possible mechanism on the sinoatrial node cells of neonat......

Sphingosine-1-phosphate (S1P) has diverse biological functions acting inside cells as a second messenger toregulate cell......

Prostaglandin E-2(PGE(2)) is a well-known mediator of beta-cell dysfunction in both type 1 and type 2 diabetes.We recent......

Stimuli-responsive polymers have undoubtedly been of great interest in the past decades due to a variety of their potent......

Objective Elevation of reactive oxygen species (ROS), especially the level of superoxide is a key event in many forms o......

Free fatty acids are known to play a key role in promoting loss of insulin sensitivity in type 2 diabetes mellitus but t......

Objectives Heart failure (HF)is one of the most common outcome for all kinds of heartdiseases, the effects of energetic ......

Recent studies have suggested that antibodies can catalyze the generation of unknown oxidantsincluding hydrogen peroxid......

Background and objectives Proliferation of human vascular smooth muscle cells (VSMCs) induced by hyperinsulinemia is a v......

Objective To explore the diagnostic value of intracellular antibody combination in acute leukemia (AL) expressing cross-......

Aim:The enhancement of intracellular Ca~(2+) signaling in response to α_1-adrener-gic receptor (α_1-AR) stimulation i......

Infection with Chlamydia trachomatis induces inflammatory pathologies in the urogenital tract that can lead to infertili......

钆离子的配合物作为核磁共振造影增强剂在临床诊断中得到广泛应用。晚期肾病患者多次大剂量使用钆造影剂后,可能发生肾源性系统纤......

Objective To study the effects of 1,25-dihydroxyvitamin D3on high-induced expression of uncoupling protein 2 and oxidati......

Elevated oxidative stress(OS)during aging leads to bone loss.OS increases intracellular Ca2+([Ca2+]i),resulting in cellu......

AIM:To investigate the cytotoxic mechanism of caribbean maitotoxin(MTX-C) in mammalian cells.METHODS:We used whole-cell ......

Objective To study the effect of metformin on proliferation and related genes expression of human osteoblast.Methods The......

Extracellular pH (pHe) and intracellular pH (pHi) are important factors for the excitability of chemosensitive central r......

Agonistic AT1 receptor autoantibodies (AT1-AAs) have been described in the patients with malignant hypertension or preec......

Calcium release from sarcoplasmic reticulum (SR) though Ryanodine receptors plays an important role in excitation contra......

Type 2 diabetes is frequently associated with both extracellular and intracellular magnesium(Mg) deficits. A chronic lat......

Prorenin receptor(PRR) is a multi-functioning protein possessing at least four different roles:(1) working as a receptor......

Objective There is little knowledge on whether there is clustering of inflammatory biomarkers, such as C-reactive protei......

Objective To investigate the effect and discuss its potential mechanism of sirolimus induced calcium overload and apopto......

AIM:The goal of this study was to characterize the AFPreceptor,its possible signal transduction pathway and itsprolifer......

AIM:TO investigate the resistance mechanism of 5-fluorouracil(5-FU)in Bel_(7402)/5-FU cells which was establishedin our......

Cardiac arrhythmias are among the most common causes of death in the world. Foundational studies established the critica......

Estradiol (E2) is the major molecular form of estrogens. Its biological effects are determined by estrogen receptors and......

AIM:To investigate the correlation between subcellulardaunorubicin distribution and the multidrug resistancephenotype i......