Pygopus-2 over-expression has been reported in several malignancies,such as ovarian,breast,lung and liver cancers.Here w......

Psoriasis is a refractory immune-mediated skin disease,and the discovery of anti-psoriatic drugs with high effectiveness......

Reactive oxygen species(ROS) originating from the NADPH oxidases AtrbohD and AtrbohF play an important role in abscisic ......

Recent studies have shown that PD-1/PD-L1 checkpoint blockade is a dramatic therapy for melanoma through enhancing antit......

As one of the top severe malignant tumors, lung cancer leads to millions of death in humans every year. However, up to d......

In order to construct plasmid of hypoxia-inducible factor-lalpha (HIF-1α), and transfect into human lung cancer cells A......

AIM:To estimate whether STI571 inhibits the expressionof vascular endothelial growth factor(VEGF)in thegastrointestinal......

AIM: To investigate the expression of genes involved in the gemcitabine-induced cytotoxicity in human pancreatic cancer ......

Objective To explore the mechanisms by which genistein and daidzein inhibit the growth of prostate cancer cells. Methods......

Objectives To investigate the effect of telmisartan on human umbilical vein endothelial cells(HUVEC) exposed to high glu......

Aberration of lipid storage in lipid droplets (LD) has been linked with the development and progression of several commo......

AIM:To explore the effect of sophocarpine on experimental liver fibrosis and the potential mechanism involved.METHODS:So......

A series of experimental methods including 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bro-mide (MTT) test,alk......

Our previous study showed that when glutamate receptor(Glu R)6 C terminus-containing peptide conjugated with the human i......

AIM: To evaluate preventative effects of ischemic preconditioning(IP) in a rat model of intestinal injury induced by isc......

AIM: To investigate the influence of lipopolysaccharide(LPS) through the p38/c-Jun N-terminal kinase(JNK)signalling path......

AIM: To investigate the effect of carvedilol on angiogenesis and the underlying signaling pathways.METHODS: The effect o......

<正> The multiplicity of opiate receptors has turned out to be the most attractive to workers in this field, since Marti......

TW19 is a diterpene compound isolated from the root cortex of Tripterygium Wil- fordii Hood. F.. Its effects on the i......

Background Several clinical studies have shown that smoking in asthmatics and chronic obstructive pulmonary disease pati......

Objective:The aim of our study was to investigate the effect of bortezomib in combination with arsenic trioxide(As2O3) o......

Objective:The aim of our study was to investigate the relationship between cell apoptosis and dephosphorylated RB protei......

Objective:The aim of our study was to investigate the biological effects of Bcl-XL antisense oligodeoxynucleotide(ASODN)......

Signal transducer and activator of transcription factor 3(STAT3)is a transcription factor that regulates various cellula......

AIM:To compare the impact of ErbB2 on cell invasion and proliferation in cholangiocarcinoma(CCA) cell lines.METHODS:Leve......

The effect of calcium chloride (CaCl2) on rice seedling growth under cadmium chloride (CdCl2) stress, as well as the pos......

Colored cotton has naturally pigmented fibers.The mechanism of pigmentation in cotton fiber is not well documented.This ......

Objective:To examine the effects of Sapium ellipticum(SE) leaf extract on the hepatic activities of glucokinase and gluc......

Nuclear factor NF-KB is believed to play an important role in regulating the production of matrix met-alloproteinases (......

Selective hydrogenation of α, β-unsaturated aldehydes with modified Pd/C catalyst was developed.The reduction of C=O b......

Electrocrystallizations of copper from both CuCl_2 silica sol and aqueous solutions were studied by the chronoamperometr......

The effects of Fe2+ on the trimethylamine N-oxide (TMAO) demethylating activity of the Harpadon nehereus kidney extract ......

A polyhedral oligomeric silsesquioxane-[60]fullerene (POSS-C60) dyad was designed and used as a novel electron acceptor ......

The prenent study was designed to test the hypothesis that the inhibitory effect of elevated glucose levels on mesangial......

It was recently reported that arsenic trioxide (As_2O_3) can induce complete remission in patients with acute promyeloc......

The gene product Sll1127 is a predicted 1,4-dihydroxy-2-naphthoyl-CoA synthase catalyzing an intramolecular Claisen cond......

The title compound bis-(1,1’-benzotriazoly)-α,ω-decoyldiamide was synthesized by the reaction of benzotriazole with s......

Objective:To explore the effects of the extract from Phyilanthus urinaria L.on hepatitis B virus(HBV) replication and ex......

Objective: To evaluate the effect of Xuefu Zhuyu Capsule(血府逐瘀胶囊)-containing serum(XFZY-CS) on Eph B4/ephrin B2 and......

Objective:To investigate the effect of Yishen Jiangzhuo Granules(益肾降浊冲剂,YSJZG) on mitochondrial injury and regener......

Objective:To investigate the anti-tumor activity and molecular mechanism of Tonglian Decoction(通莲汤,TLD) on esophageal......

Water pollution has become serious environmental problem nowadays. Advanced oxidation processes(AOP) have been widely ap......

AIM: To examine the possible ameliorative effect of breastfeeding and the uptake of human colostrum against coeliac dise......

Here, we introduce the design of the structure of RR(RYYAAFFARR), an inhibitor of Aβ aggregation, using molecular docki......

Objective To study the effects of melatonin on pethidine-induced physical dependence and its antioxidative action.Method......

Objective To investigate the spasmolytic and anti-diarrheal activities of 3,4-dihydro-2-(4-morpholinylmethy)-1(2H)-napht......

The effect of benzimidazole units on thermal imidizaiton was studied when they were introduced into the main chain of po......

Objective:To investigate the effects of rosiglitazone,a synthetic ligand of peroxisome proliferators-activated receptor ......

Discovery and functional identification of plant-derived small compounds as the immunosuppressant attract much attention......

A series of SBA-15 supported bimetallic Rh–Ni catalysts with different weight ratio of Rh/Ni in the range of 0–0.04 we......