MICROGLIA相关论文
目的:探讨前额叶皮质区小胶质细胞活化对卒中后抑郁小鼠远期空间记忆功能的影响。方法:取48只C57BL/6雄性小鼠按照随机数字表法分......
背景白细胞介素10（IL-10）是一种重要的抗炎细胞因子,可以促进神经元和神经胶质细胞的存活,IL-10缺失,引起了阿尔茨海默症（AD）小鼠模型......
缺血性脑卒中是一种血液循环障碍疾病,可导致严重的神经功能缺损.卒中病人中约有87％的病例为缺血性卒中.神经炎症是中风损伤的主要......
目的：:探讨小胶质细胞在急性光诱导小鼠视网膜损伤中的保护作用。方法：:实验研究。将30只雄性ICR白化小鼠随机均分为对照组、光损伤......
目的:评价长期摄入ω-3多不饱和脂肪酸(ω-3 PUFAs)对术后认知功能障碍(POCD)小鼠海马小胶质细胞活化的影响。方法:清洁级健康雄性......
目的:评价肝缺血再灌注大鼠外泌体对小胶质细胞焦亡的影响。方法:清洁级健康雄性SD大鼠20只，2~3周龄，体重20~50 g，采用随机数字表法分......
Inflammatory responses,including glial cell activation and peripheral immune cell infiltration,are involved in the patho......
The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 p
Extracellular vesicles (EVs) from mesenchymal stromal cells (MSCs) have previously been shown to protect against brain i......
Recent findings have implicated inflammatory responses in the central nervous system in a variety of neuropsychiatric an......
目的:评价内侧前额叶皮质(mPFC)小胶质细胞P2Xn 7受体在大鼠神经病理性痛中的作用及其与自噬的关系。n 方法:SPF级健康成......
Dlg1 Knockout Inhibits Microglial Activation and Alleviates Lipopolysaccharide-Induced Depression-Li
Microglia-mediated neuroinflammation is widely perceived as a contributor to numerous neurological diseases and mental d......
Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing sp
Accumulating evidence shows that agents targeting gut dysbiosis are effective for improving symptoms of irritable bowel ......
Background::Microglia plays an indispensable role in the pathological process of sleep deprivation (SD). Here, the poten......
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Reducing host aldose reductase activity promotes neuronal differentiation of transplanted neural ste
Neural stem cell (NSC) transplantation is a promising strategy for replacing lost neurons following spinal cord injury. ......
Myeloperoxidase is an important inflammatory factor in the myeloid system, primarily expressed in neutrophils and microg......
After spinal cord injury,microglia as the first responders to the lesion display both beneficial and detrimental charact......
Microglia activation, classification and microglia-mediated neuroinflammatory modulators in subarach
Subarachnoid hemorrhage is a devastating disease with significant mortality and morbidity, despite advances in treating ......
Long noncoding RNAs (lncRNAs) participate in many pathophysiological processes after traumatic brain injury by mediating......
Striatal oxidative damages and neuroinflammation correlate with progression and survival of Lewy bod
Neurodegenerative diseases are a class of chronic and complex disorders featuring progressive loss of neurons in distinc......
Exposure to explosive shockwave often leads to blast-induced traumatic brain injury in military and civilian populations......
Retinitis pigmentosa is a retinal disease characterized by photoreceptor degeneration. There is currently no effective t......
Profile of the RNA in exosomes from astrocytes and microglia using deep sequencing: implications for
Glial cells play an important role in signal transduction, energy metabolism, extracellular ion homeostasis and neuropro......
The discovery that new neurons are produced in some regions of the adult mammalianbrain is a paradigm-shift in neuroscie......
The phenotypic convergence between microglia and rperipheral macrophages during development and rneu
Microglia, the tissue resident macrophages of the brain, are increasingly recognized askey players for central nervous s......
A major feature of neurodegeneration is disruption of central nervous system homeostasis, during which microglia play di......
Astrocytes are integral components of the central nervous system, where they are involved in numerous functions critical......
Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfu
We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-like receptors (TLR) ......
Guanosine-5′-triphosphate cyclohydrolase 1 regulated long noncoding RNAs are potential targets for m
Several studies have confirmed that microglia are involved in neuropathic pain. Inhibition of guanosine-5′-triphosphate......
Electroacupuncture Attenuates Spinal Nerve Ligation-Induced Microglial Activation Mediated by p38 Mi
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Effect of Chinese Herbal Compound Naofucong(脑复聪) on the Inflammatory Process Induced by High Glucose
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Effects of Electroacupuncture Intervention on Expression of Cyclooxygenase 2 and Microglia in Spinal
Objective:To investigate the effect of electroacupuncture (EA) treatment on the expression of cydooxygenase (COX) 2 and ......
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Effects of Flower Buds Extract of Tussilago farfara on Focal Cerebral Ischemia in Rats and Inflammat
Objective:To investigate the effects of the flower buds extract of Tussilago faffara Linné (Faffarae Flos;FF) on focal ......
Extract of Fructus Schisandrae chinensis Inhibits Neuroinflammation Mediator Production from Microgl
Objective:To investigate the anti-neuroinflammation effect of extract of Fructus Schisandrae chinensis (EFSC) on lipopol......
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Aquaporin-4 deficiency attenuates acute lesions but aggravates delayed lesions and microgliosis afte
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Immunopotentiator Thymosin Alpha-1 Promotes Neurogenesis and Cognition in the Developing Mouse via a
In early life,the immune system plays an essential role in brain development.In our study,the immunopotentiator thymosin......
Chronic pain and itch are a pathological operation of the somatosensory system at the levels of primary sensory neurons,......
Sex-Dependent Glial Signaling in Pathological Pain: Distinct Roles of Spinal Microglia and Astrocyte
Increasing evidence suggests that spinal microglia regulate pathological pain in males.In this study,we investigated the......
Overexpression of Purinergic P2X4 Receptors in Hippocampus Rescues Memory Impairment in Rats with Ty
Purinergic receptors have been reported to be involved in brain disorders.In this study,we explored their roles and mech......
Activation of inflammatory responses regulates the transmission of pain pathways through an integrated network in the pe......
Up-regulation of P2X7 Receptors Contributes to Spinal Microglial Activation and the Development of P
Previous work has demonstrated that the sensitization of spinal neurons and microglia is important in the development of......
Ischemic stroke is a leading cause of morbidity and mortality worldwide.Resident microglia are the principal immune cell......
Microglia-Derived NLRP3 Activation Mediates the Pressor Effect of Prorenin in the Rostral Ventrolate
Increased microglial activation and neuroinflammation within autonomic brain regions such as the rostral ventrolateral m......
MiR-30a Positively Regulates the Inflammatory Response of Microglia in Experimental Autoimmune Encep
Multiple sclerosis (MS) is a classical inflammatory demyelinating disease of the central nervous system (CNS).Microglia ......
Purpose: To evaluate the effects of γ-secretase inhibitor treatment after transient cerebral ischemia using magnetic re......
Microglia are important resident immune cells in the central nervous system(CNS)and involved in the neuroinflammation ca......
