Neuroprotective相关论文
Objective AD is the most common form of dementia among older people.Recent studies have demonstrated that melatonin may ......
Aim: An attempt has been made to explore the neuroprotective and antitremor effect of baicalein on neurons against exper......
Objective For investigating whether overexpression of PDZ1 domain of PSD-95 can inhibit apoptosis in neurons induced by ......
Aim: To investigate the neuroprotective effects of Tenuifoliside A (TFSA) on corticosterone-induced injury in rat glioma......
Acetylated chitosan oligosaccharides act as antagonists against glutamate-induced PC12 cell death vi
Chitosan oligosaccharides (COSs), depolymerized products of chitosan composed of β-(1→4) D-glucosamine units, have bro......
Liquiritigenin inhibits amyloid β-peptide-induced neurotozicity,the secretion of amyloid β-peptide a
Background and Purpose: Amyloid β-peptide(AP) is a pivotal pathological factor in Alzheimers disease(AD). Estrogen is b......
Design,Synthesis and Biological Evaluation of Pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione Derivativ
A series of pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione derivatives was designed and synthesized,and their neuroprotect......
Parkinsons disease (PD) is one of the most prevalent neurodegenerative diseases characterized by accumulation of α-......
虾青素是一种脂溶性的强抗氧化剂,它能透过血脑屏障,通过其强大的抗氧化和抗炎症作用来保护神经元。虾青素也能影响神经元凋亡相关的......
Soybean andtempeh total isolfavones improved antioxidant activities in normal and scopolamine-induce
本文通过对荣华二采区10...
本文通过对荣华二采区10...
BACKGROUND: Neural regeneration fol owing nerve injury is an emerging field that attracts ex-tending interests al over t......
[Objectives]To explore the neuroprotective effects and mechanism of Longan Aril(LA)effective parts on PC12 cells injured......
Mangiferin exerts neuroprotective activity against lead-induced toxicity and oxidative stress via Nr
Objective:The study was designed to assess the beneficial role of mangiferin (MGN) in lead (Pb)-induced neurological dam......
Neuroprotective effect of Paeoniae Radix Rubra on hippocampal CA1 region of mice induced by transien
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Damage from spinal cord injury occurs in two phases – the trauma of the initial mechanical insult and a secondary injur......
目的 现对急性脑梗死患者的雌二醇水平和脑血管病的相关危险因素进行观察,探讨雌二醇与缺血性脑血管病的关系.方法 选取100例绝经......
A new series of compounds(E)-1-(4-(bis-arylmethyl)piperazin-l-y1)-3-arylprop-2-en-1-one(1a-r),have been synthesized and ......
目的研究番茄红素对β-淀粉样蛋白(Aβ)42转基因果蝇的神经保护作用。方法将实验果蝇随机分为不同浓度干预组、二甲基亚砜(DMSO)溶剂对......
目的:观察天麻素(GAS)对百草枯(PQ)和代森锰(MB)致小鼠黑质多巴胺(DA)能神经元损伤的神经保护作用及其机制。方法:用PQ和MB建立C57BL小鼠PD模......
目的:探讨腹腔镜中低位直肠癌根治术经"Holy plane"间隙保留盆自主神经的疗效。方法:把实施了经"Holy plane"间隙保留盆自主神经中低位直......
Current experimental stroke research has evolved to focus on detailed understanding of the brain’s self-protective and ......
目的:阐明灯盏细辛脑保护作用机理。方法:检索中国期刊全文数据库2005-2010年关于灯盏细辛脑保护作用的相关文章。结果:灯盏细辛的......
脑需连续供氧和葡萄糖,这是通过调节脑血液循环来完成的.当患有中风和脑缺血(cerebral ischemia)等疾病时则供应不足.现用的脑血管......
目的探讨三七总皂苷对实验性高眼压导致的大鼠视网膜神经节细胞层(RGCL)神经元损伤有无保护作用。方法健康SD大鼠42只,其中6只为正常......
目的探讨孕酮对大鼠局部脑缺血/再灌注损伤的神经保护作用及机制。方法将大鼠随机等分为假手术组、正常对照组、孕酮组、溶剂(DMSO)......
目的探讨补阳还五汤在脑出血恢复期的疗效。方法选取200例脑出血恢复期患者,中医辨证属于气虚血瘀型,随机分为治疗组100例与对照组......
Dopamine (DA) agonists are playing increasingly important role in the treatment of not only advanced Parkinson′s diseas......
目的研究丙戊酸钠(VPA)对托吡酯(TPM)神经保护作用的影响。方法将3~4周龄雄性Wistar大鼠48只,随机均分为4组。A组为阴性对照组,B为阳性......
Nepfilysin(NEP)是M13锌金属蛋白酶家族的一种Ⅱ型整合细胞膜糖蛋白.自从1974年首次被定义以来,NEP作为一种神经肽的降解酶,已经被发现......
Antidepressants with novel targets and without side effects are in great demand. Ferulic acid (FA) is a ubiquitous pheno......
虾青素是目前备受关注的一种叶黄素类胡萝卜素,是一种脂溶性的的萜烯类不饱和化合物,可以通过强大的抗氧化性和抗炎作用起到保护神......
Ginseng is a traditional Chinese medicine with a long medicinal history.Ginsenoside is the main compo nent of ginseng,am......
The effect of Batroxobin expression of neural cell adhesion molecule (NCAM) in left temporal ischemic rats with spatial ......
乳铁蛋白(Lf)是一种铁结合性糖蛋白,分子量为80kDa,是转铁蛋白家族的成员。Lf属于一种多功能蛋白,具有促进肠道内铁吸收、抗癌、抗......
Preliminary in vitro evaluation of neuroprotective and monoamine oxidase type B inhibitory effects o
The expected growth of the elderly population at highest risk for Parkinson’s disease(PD)in the next decades makes the ......
Alzheimer's disease (hereafter AD) is a progressive neurodegenerative disorder that affects the central nervous syst......
Emerging evidence implicates that SIRT1,one of NAD-dependent protein deacetylase,is involved in the regulation of neuron......
Batroxobin Against Anoxic Damage of Rat Hippocampal Neurons in Culture: Morphological Changes and Hs
Batroxobin,the thrombin-like enzyme,is used for therapeutic defibrination. We have found that batroxobin has good therap......
We have found that Batroxobin plays a protactive role in ischemic brain injury, which attracted us to investigate the ef......
Alkaloids are a class of natural products with a wide range of biological activities. Due to the special living environm......
Oleanolic acid(OA)and its derivatives are widely found in diverse plants and are naturally effective pentacyclic triterp......
Structural and functional characterization of a novel ShK peptide and its analogue from zoanthids (c
OBJECTIVE To identify and characterize a novel neuroprotective ShK peptide and its analogue originated from coral P. car......
Evodiamine derivatives improve cognitive abilities in APP~(swe)/PS1~(ΔE9) transgenic mouse models of
Background: Alzheimer's disease(AD) is a complex neurodegenerative disease. Due to the complexity of its molecular p......
Isolation and Neuroprotective Activity of Phenolic Derivatives from the Marine-Derived Fungus Penici
A new phenolic compound, 6-(2-acetyl-3,5-dihydroxybenzyl)-4-hydroxy-3-methyl-2H-pyran-2-one(1), along with other six kno......
Neuroprotective Effects of Ginkgo Biloba Extract (GbE) on Oxygen-Glucose Deprivation (OGD) in PC12 C
Ischemic cerebrovascular disease is a global health problem. According to the World Health Organization, ischemic stroke......
Paeoniflorin(PA) is an anti-Parkinson Chinese medicine with inferior bioavailability and difficulty in delivery to the b......
New neuroprotective perspectives in fighting oxidative stress and improving cellular energy metaboli
Neurodegenerative diseases are a heterogeneous group of disorders characterized by a progressive dysfunction and death o......
OBJECTIVE Brahmi(Bacopa monnieri Wettst.,Schrophulariaceae)has been used in Ayuravedic medicine as a memory enhancer.We ......