PH-SENSITIVE相关论文
One of challenge for cancer therapy is efficient delivery of anticancer agents into tumor sites to increase the efficien......
A pH-sensitive nanopolysaccharide-based micelles as vaccine adjuvant for enhancing anti-cancer immun
Cancer vaccine has been considered as a potential therapeutic strategy to enhance the cancer treatment.Retinoic acid(RA)......
pH-sensitive docetaxel-loaded TPGS-poly(β-amino ester) copolymer nanoparticles for overcoming multid
Multidrug resistance (MDR) is one of the major obstacles to successful chemotherapy.Overexpression of drug efflux transp......
pH-Sensitive Polymeric Nanoparticles with Gold(I)Compound Payloads Synergistically Induce Cancer Cel
Various nanomaterials have been demonstrated as autophagy inducers owing to their endocytosis cell uptake pathway and im......
Hydrogels represent a promising technology platform for therapeutic intervention in a variety of diseases due to their c......
pH-triggered charge-reversal and redox-responsive nanoparticles for docetaxel delivery in hepatocell
The insufficient cellular uptake of nanocarriers and their slow drug release have become major obstacles for achieving s......
Glycyrrhetinic Acid-Conjugated pH-Responsive Polymeric Micelles as Drug Carriers for Targeted Treatm
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A pH-Sensitive Nano Doxorubicine Delivery System from Amphiphilic Polyrotaxane-based Triblock Copoly
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Temperature and pH value are two significant parameters to assess ones physical health.Significant efforts have been dev......
Polycationic gene delivery system was widely used for cancer therapy.Polycations with high positive potentials exhibited......
Gene therapy has played great roles in many disease treatments including cancer therapy.However,inefficient intracellula......
Lysosomal disruptive nanocarrier based on pH-sensitive charge-reversal for tumor targeted anticancer
Lysosomal disruption and escape ability is critically important to protect entrapment of drugs and acquire maximum thera......
Doxorubicin-conjugated magnetic iron oxide nanoparticles for pH-sensitive and magnetic responsive dr
Many nano-sized inorganic materials have specific properties upon exposure to light,electricity and magnetism and their ......
Nucleolin targeting AS1411 aptamer modified pH-sensitive micelles: a dual-functional strategy for pa
Targeted drug delivery coupled with rapid drug release in cytoplasm is a powerful strategy to enhance efficacy and reduc......
Targeted hepatoma chemotherapy in vivo using galactose-decorated crosslinked pH-sensitive degradable
The successful cancer chemotherapy relies on the development of smart nanocarriers that are highly stable in circulation......
Effect of molecular adjuvant inclusion in pH-sensitive polymer-modified liposomes on their performan
Cancer immunotherapy requires effective antigen carriers to deliver antigen into the cytosol of dendritic cells (DCs),wh......
A novel hydrogel was obtained by graft copolymerization of acetic acid lignin(AAL,isolated from the black liquor produce......
Acidic extracellular/intracellular pH is a universal phenomenon in solid tumors regardless of the tumor type or stage[1]......
Synergistic therapeutics have been demonstrated as means for effective tumor therapy,while the co-loading of cargoes wit......
Microstructured fluorescent biosensor based on energy migration for selective sensing of metalloprot
Fluorescent microspheres consisting of a conjugated phenylenevinylene 3B2B doped with a fluorenone derivative DSFO were ......
We have been exploiting inherent tumor properties in the delivery of anticancer therapeutic materials and aimed specific......
Integrated therapy on residual tumor after palliative operation using dual-phase drug releasing elec
Cancer is a leading cause of death worldwide and surgery remains the most effective treatment for the majority of cancer......
pH-sensitive polysaccharide derivatives-modified liposomes as antigen delivery vehicles for cancer i
For establishment of cancer immunotherapy,efficient antigen carriers are needed to deliver antigen into the cytosol of d......
Supramolecular assembly is attracting a lot of attention as multifunctional nanoparticles can be prepared by using diffe......
Self-assembled amphiphilic sequence-defined PEGylated three-arm oligo(ethanamino)amides via NCL reac
Many therapeutic anticancer drugs,such as doxombicin (DOX),are limited in their clinical applications due to their serio......
Preparation of Charge-conversion nanoconjugates based on Poly(β-L-malic acid) for effective and spec
The tumor extracellular environment is more acidic than normal tissues.Therefore,pH-dependent charge conversion systems ......
pH-sensitive polymeric nanocarriers look like the most promising tool for cancer therapy[1,2].In this work,novel pH-sens......
pH-responsive nanoparticles based on algal polysaccharide for co-delivery of celecoxib and doxorubic
Objective Metastasis and chemotherapy resistance are the leading causes of breast cancer mortality.Celecoxib(CXB)has ant......
Self-adjuvanted nanovaccine for cancer immunotherapy: Role of lysosomal rupture-induced ROS in MHC c
MHC class Ⅰ (MHC Ⅰ) antigen presentation of exogenous antigens (so called "cross presentation") is a central mechani......
pH-Sensitive Drug Release in Enhancing Cytotoxicity Mediated by Chitosan based Glycolipid-like Nanoc
In our previous study, we can delivery drug to specific issues and cells.However, the problems of drug release in tumor ......
Our study is to establish tumor pH-sensitive magnetic nanogranades (PMN) composed of pH-responsive ligands and iron oxid......
pH-sensitive charge-reversal pullulan derivative and poly(β-amino) ester-containing nanoparticles fo
Objective: Pullulan is a non-toxic, non-mutagenic and water-soluble natural polysaccharide produced from aureobasidium p......
The pH-responsive micelles for the delivery anticancer agents have been found great potential in the past decade.Usually......
Rational design of vaccine adjuvants may provide protective immunity against infective diseases through immune-stimulati......
Objective: Osthol-loaded Eudragit S100 nanoparticle (Ost-S 100-NP) is a novel pH-sensitive nanparticle that are prepared......
Bone is a major organ of metastasis for many kinds of tumor, particularly for prostate and lung cancer.Although the bone......
Synthesis, preparation and potential drug carrier of multifunctional targeted nano-carrier drug deli
Many studies about HA and its derivatives were reported, which can be devided into two types.One type was HA-drug conjug......
Synthesis and characterization of low-density lipoprotein modified poly-N-succinyl chitosan lipoic a
Objective: In this paper, we report on reduction and pH dual-sensitive reversibly core-crosslinked micelles based on N-s......
In this study, our aim was to develop an injectable drug reservoir to provide sustained, pH-sensitive curcumin-loaded ke......
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pH-sensitive platform using lipid-enveloped Zinc Phosphate nanoparticlesfor tumor lysate delivery an
Over the past few years,immunotherapy has been developed vigorously and become the fourth modality pillars of cancer the......
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Preparation of polyaspartic acid-ethylcellulose blend hydrogel for controlled release of naproxen so
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Hypochlorous acid(HClO) plays a powerful fungicide role in the innate immune system.It is produced by H2O2 and Cl-in res......
