Tumorigenicity相关论文
Objective Osteosarcoma is the most common primary malignant tumor of bone that most commonly affects children,adolescent......
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Target Regulate Cell Proliferation and Tumorigenicity through Different Genes between Normal Human R
Purpose Although stem cell replacement therapy provide a prospective treatment for neural blindness,there are still fund......
Effects of upregulation of Id3 in human lung adenocarcinoma cells on proliferation, apoptosis, mobil
Objectives:The inhibitor of DNA binding/differentiation 3 (Id3) protein is a helix-loop-helix transcription factor and m......
Objective: To investigate the characteristics of breast cancer stem cells and their protein expression of RecQ family he......
Prostate specific membrane antigen knockdown impairs the tumorigenicity of LNCaP prostate cancer cel
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Serum soluble suppression of tumorigenicity 2 as a novel inflammatory marker predicts the severity o
BACKGROUND Acute pancreatitis(AP)is an inflammatory disease in which the regulatory pathway is complex and not well unde......
目的 探讨HCT116细胞和HCT116球细胞的成瘤能力及其蓬乱蛋白3(dishevelled 3,DVL3)的表达.方法 采用无血清培养法培养人结直肠癌HC......
目的探讨EB病毒mir-BART5可促进鼠成纤维细胞恶性表征的作用机制。方法生物信息学分析显示miR-BART5与miR-18序列相近,miR-18的靶......
Inhibition of cervical cancer cell proliferation and cervical tumorigenicity caused by farnesoid X r
OBJECTIVE Cervical cancer is the third most malignant tumor in the world.Farnesoid X receptor(FXR) is a member of nuclea......
Further Report on Carcinogenesis or Tumorigenicity of MDCK Canine Kidney Cell(CKC) Lines and Analysi
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Background Cyclin B1 (CLB1) is necessary for mitotic initiation in mammalian cells and plays important roles in cancer d......
OBJECTIVE Over-expression of transforming growth factor β1 (TGF-β1) has been observed in many advanced cancers.The pre......
A novel lncRNA, Lnc-OC1, promotes ovarian cancer cell proliferation and migration by sponging miR-34
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Malignant Transformation and Abnormal Expression of Eukaryotic Initiation Factor in Bronchial Epithe
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Human IL-6 gene was transduced into FBL-3murine erythroleukemia cells in vitro by calcium phosphate co-participation. Af......
An RNA-seq-based Gene Expression Profiling of Radiation-induced Tumorigenic Mammary Epithelial Cells
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Pyrrolizidine alkaloids are a class of hepatotoxic and tumorigenic compounds detected in Chinese herbal plants, contamin......
Malignant Transformation and Abnormal Expression of Eukaryotic Initiation Factor in Bronchial Epithe
To analyze the relationship between malignant transformation and abnormal expression of eukaryotic initiation factor 3 (......
Background Cyclin B1 (CLB1) is necessary for mitotic initiation in mammalian cells and plays important roles in cancer d......
目的探讨胰腺癌细胞(PC-3)胰岛素样生长因子-1受体(IGF-1R)基因的定量表达,及其与细胞凋亡、成瘤性的关系.方法用逆转录PCR方法,检......
Preliminary evidence that overexpression of nuclear factor for IL6 expression (NF—IL6) in NIH3T3 cel
NF-IL6 is a member of c/EBP family and has multiple functions in regulation of cellular gene expression.We have construc......
INDUCTIONOFIMMUNERESPONSEBYIL6GENEMODIFIEDLEUKEMIACELLSCaoXuetao曹雪涛GeLingfu葛林阜JuDianWen鞠佃文YuYizhi于益芝TaoQun陶群ZhangWeiping章卫.........
DIFFERENTIAL EXPRESSION OF GENES INVOLVED IN METABOLISM BETWEEN TUMORIGENITIC HUMAN LEUKEMIA CELL LI
Objective: To study the molecular mechanism of different tumorigenicity in nude mice of human leukemia cell lines K562-n......
目的肾胚瘤是一种较常见的儿科实体肿瘤,该肿瘤的发生与抑癌基因WT1密切相关.本研究的目的是利用脂质体介导转染法将WT1cDNA导入G4......
目的:依据人大肠癌细胞HCT-15的表面标志物,分离其中的干细胞亚群。建立裸鼠体内原代大肠癌荷瘤模型,比较各亚群肿瘤体积和质量。方......
AIM:To investigate the association of p42.3 expression with clinicopathological characteristics and the biological funct......
目的 比较体外软琼脂克隆法与裸鼠体内接种法检测细胞致瘤性的敏感性及相关性.方法 用软琼脂克隆法检测不同种类、不同来源的细胞......
Further Report on Carcinogenesis or Tumorigenicity of MDCK Canine Kidney Cell(CKC) Lines and Analysi
Using Hela cell cultures as positive control and primary canine kidney cell (CKC) or feline kidney cell (FKC) cultures p......
Objective To analyze the relationship between malignant transformation and abnormal expression of eukaryotic initiation ......
探讨突变的膜结合型TNF-α基因对人胃癌细胞生长的影响,方法:用突变的膜结合型TNF-α基因作为目的基因,以逆转录病毒为载体将目的基因导入人胃......
2013年WHO生物制品标准化专家委员会发布了最新版的动物细胞基质生产生物医药产品和细胞库特性的评价建议(Recommendations for th......
目的检测High Five昆虫细胞系对BALB/c裸鼠致瘤性情况,以确保其作为疫苗生产细胞株的安全性。方法将裸鼠随机分为5组,分别为High F......
目的:观察转入TNFα基因对肾细胞癌细胞(RCC)致瘤性的影响,为进一步对RCC的基因治疗打下基础。方法:将人TNFα基因构建入逆转录病毒载体......
目的:研究细胞介素2(IL-2)、白细胞介素3(IL-3)基因共转染瘤苗的体现人外生物学特性。方法:用IL-2重组腺病毒(Ad-IL-2)、IL-3重组腺病毒(Ad-IL-3)转染FBL-3红白血病细胞株,观察其体外......
目的:探索K562和K562-n细胞在裸鼠体内致瘤性不同的分子生物学机制.方法:应用基因芯片技术,检测K562细胞和K562-n细胞的差异表达基......
目的:探讨人白血病细胞系K562-n和HL60-n在裸鼠体内高致瘤性的细胞遗传学机制.方法:对裸鼠体内致瘤性不同的K562细胞、K562-n细胞......
Pyrrolizidine alkaloids are a class of hepatotoxic and tumorigenic compounds detected in Chinese herbal plants,contamina......
【Abstract】In vitro proliferation and in vivo tumorigenicity of IL-2 and/or IL-3 gene transfected FBL-3erythroleukemia ......
目的:明确S100 A16在前列腺癌中的表达水平,并探讨它在前列腺癌细胞侵袭中的作用及分子机制。方法:利用Western blot和免疫组化的方法......
目的探索高致瘤性K562-n细胞系在胸腺缺陷裸小鼠体内致瘤的细胞生物学机理.方法通过极限稀释法建立K562-n细胞系致瘤率不同的克隆......
探讨小鼠肉瘤S-180细胞转IL-2基因后是否存在细胞功能改变。通过MTT试验,流式细胞仪分析及电镜观察,结果提示IL-2基因转染影响S-180细胞的增殖活性,细胞周期......
目的观察姜黄素在体内对人肝癌细胞株SMMC-7721的抗肿瘤作用。方法用姜黄素在SMMC-7721肝癌细胞荷瘤裸鼠的瘤体内进行注射治疗,12 ......
The recombinant PSG5-RARβ plasmid and the G418 resistant PSVzneo plasmid (10:1) were cotransfected into PGCL3 cells by ......
目的 研究人脐带间充质干细胞(hUCMSCs)对动物是否具有促瘤性,以及不同代次是否有致瘤性,为其临床应用提供安全性依据。方法 分别用......
肿瘤的发生发展包括肿瘤细胞的体内成瘤性、异种移植肿瘤的生长、血管生成、肿瘤迁移侵袭及转移等过程,而成瘤性相关蛋白在此过程......