immunogenicity相关论文
Thesevereacuterespiratorysyndromecoronavirus2(SARS-CoV-2)infectionhasresultedinnumerousconfirmedcasesanddeathsworldwide.......
Although abscopal tumor regression remained a rare phenomenon.We generated two distinct tumor models stratified as highl......
目的:评价维持性血液透析（MHD）患者接种重组戊型肝炎疫苗的安全性和免疫原性。方法:采用开放对照试验法，于2016年5月至2018年3月在厦......
Severe fever with thrombocytopenia syndrome (SFTS), caused by a novel identified bunyavirus SFTS virus (SFTSV), was an e......
Cytosolic delivery of the immunological adjuvant Poly I:C and cytotoxic drug crystals via a carrier-
Co-delivery of chemotherapeutics and immunostimulant or chemoimmunotherapy is an emerging strategy in cancer therapy.The......
目的:观察新型冠状病毒疫苗加强免疫的免疫原性及安全性。方法:2020年10月，江苏省疾病预防控制中心（CDC）开展了新型冠状病毒灭活疫苗......
Human epididymal protease inhibitor (eppin) may be effective as a male contraceptive vaccine.In a number of studies,eppi......
Seven major genomic deletions of vaccinia virus Tiantan (VTT) is sufficient to decreased Pathogenici
Objective Attenuated strain TTVAC7 is a multi-gene-deleted vaccinia virus Tiantan strain constructed by knocking out par......
Immunogenicity of venoms from four snakes common in China and venom detection by species-specific an
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In the present study,the microneme 5 gene of Eimeria acervulina(E.acervulina)(EaMIC5)was cloned and characterized....
Selection for a precocious line of Eimeria intestinalis and the study of its pathogenicity and immun
Eimeria intestinalis is one of the most pathogenic species of coccidia which causes coceidiosis in rabbits.Live oocyst v......
Immunogenicity and protective efficacy of recombinant fusion proteins containing spike protein of in
Infectious bronchitis (IB) is an acute and highly contagious viral respiratory disease of chickens and vaccination is th......
Disulfiram Copper Complex Enhancing the Immunogenicity and Radiation Sensitivity of Esophageal cance
Objective Background: Radiation therapy plays a major role in the management of esophageal cancer.However,the radioresis......
Attenuation of the influenza virus by microRNA response element in vivo and protective efficacy agai
目的 To examined the potential of the microRNA response elements(MREs)-containing influenza A virus as a live attenuated......
Capsid Proteins from PCV2a Genotype Confer Greater Protection against a PCV2b Strain than those from
Background: Two major porcine circovirus type 2 (PCV2) genotypes, PCV2a and PCV2b, are recognized.PCV2a was predominant ......
Classical swine fever virus (CSFV) C-strain is one of the best modified live attenuated vaccines against Classical swine......
Comparative immunogenicity of hepatitis B vaccine with different dosages and schedules in healthy yo
Objectives: To compare immunogenicity of hepatitis B vaccine between the standard 3-dose(20 μg)and 2-dose with higher-d......
Evaluation of human monoclonal antibody toxicity, toxicokinetics and immunogenicity in cynomolgus mo
Aim: A human monoclonal antibody was administered intravenously for 4-week in cynomolgus monkeys.The aim of this study w......
Classical swine fever virus(CSFV)C-strain is one of the best modified live attenuated vaccines against Classical swine f......
Generation and Efficacy Evaluation of a Recombinant Pseudorabies Virus Variant Expressing the E2 Pro
Classical swine fever(CSF)is an economically important infectious disease of pigs caused by classical swine fever virus(......
Pathogenicity and immunogenicity of a gE/gI/TK gene-deleted pseudorabies virus variant in susceptibl
A pseudorabies virus(PRV)variant with enhanced pathogenicity has emerged in many vaccinated swine herds in China since 2......
Screening,purification, and identification of annexin B1 mutants with high phosphatidylserine-bindin
Annexin B1 has many potential biomedical applications based on its high affinity for negatively charged phospholipid (ph......
Effects of Fermentation by Staphylococcus xylosus on the Immunogenicity of Fish Allergen Parvalbumin
[Objective]To study the effect of fermentation by Staphylococcus xylosus on the immunogenicity of fish allergen Parvalbu......
The immunological competence of multiple antigen peptides based on the mimic epitope of Mycoplasma g
Objective To analyze the the humoral and cellular immune response levels of multiple antigen peptides (MAPs) containing ......
Enhanced anti-tumor activity of human PBMC activated by a recombinant bifunctional protein targeting
ObjectiveThe EGF-EGFR signaling pathway plays a pivot role in regulating cell proliferation,survival,metastasis,and angi......
Research on immunity response induced by intranasal immune with inactive human high pathogen avian i
Based on the pressing need for vaccines against highly pathogenic H5N1 subtype avian influenza virus,the humoral and cel......
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The amino acid sequences of human adenoviruses (HAdV) hexons from five types of HadV, type 3,7, 11, 14 and 55, were anal......
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Immunogenicity and safety of a new inactivated hepatitis A vaccine in young adults: a comparative st
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Immunogenicity and safety of a severe acute respiratory syndrome coronavirus 2 inactivated vaccine i
Background:The significant morbidity and mortality resulted from the infection of a severe acute respiratory syndrome co......
Isolation, Identification and Immunogenicity of a Chicken-derived Strain of Fowl Avidenovirus Type 4
Abstract In order to obtain a fowl avidenovirus type 4 strain with good immunogenicity， chicken liver tissues suspected o......
目的:分析HIV 感染者CD4n +T淋巴细胞（CD4）水平对乙肝疫苗免疫应答的影响，探讨不同CD4水平的HIV感染者乙肝疫苗免疫效果及其持久......
The recombination and expression of R1 repeat region of Mycoplasma hyopneumoniae P97 adhesin gene wi
Swine mycoplasmal pneumonia (SMP), caused by Mycoplasma hyopneumoniae (Mhp), is one of the most important respirator......
Immunogenicity study of an expressed Outer membrane protein A (OmpA) of Edwardsiella tarda to Japane
The outer membrane protein A (OmpA) of Edwardsiella tarda was expressed and purified after the recombinant expressio......
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目的 构建霍乱弧菌抗菌抗毒口服活疫苗候选株 ,并在家兔模型中评价它们的免疫原性及主动保护力。方法 应用染色体 质粒致死平衡......
为了解牛源犬新孢子虫AMA1基因蛋白特性及免疫原性,本试验以重组质粒PVAX1-NcAMA1为模板,PCR扩增NcAMA1基因,亚克隆至pGEX-4T-1表......
为评价佐剂对金黄色葡萄球菌（S.aureus）CP8-FnBPB-ClfA免疫效果的影响,用纯化的S.aureus血清8型荚膜多糖与FnBPB-ClfA蛋白偶联的偶联......
扩增了奶牛乳腺炎金黄色葡萄球菌ClfA基因,并将其克隆至真核表达载体pVAX1启动子下游,构建成真核表达质粒,通过体外细胞转染试验,......
Neural progenitor cells from human induced pluripotent stem cells generated less autogenous immune r
The breakthrough development of induced pluripotent stem cells(iPSCs)raises the prospect of patient-specific treatment f......
目的 观察国产冻干无佐剂Vero细胞狂犬病疫苗小剂量皮内注射的接种反应及其免疫原性.方法 对256名Ⅱ级狂犬病暴露受试者进行暴露后......
Expression of Hantaan virus 26 Kd fragment of nucleocapsid protein in insect cells and prelimimary s
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The capacity of pluri-potent stem cells to repair the tissues in which stem cells reside holds great promise in developm......
Similar Ability of FbaA with M Protein to Elicit Protective Immunity Against Group A Streptococcus C
Group A streptococcus (GAS), an important human pathogen, can cause various kinds of infections including superficial in......
目的 构建布鲁杆菌M5-90Δbp26基因缺失株,对比观察其免疫原性与M5-90亲本株的区别,研制毒力弱、安全性能好并能进行鉴别诊断的布......
目的 应用分子克隆技术获得纳米级Ag85B蛋白并对其进行鉴定和免疫学特性检测.方法 利用S-layer/Streptag I这一具有自我组装能力的......
