epigenome相关论文
Epigenetic mechanisms regulate the chromatin structure and gene expression levels without changing the primary DNA seque......
Conflicts of DNA methylation and CpG density are involved in alternative promoter usage and genome s
The pattern of DNA methylation is shaped by different factors including CpG dinucleotide density.To globally evaluate th......
Huntingtons disease (HD) is an inherited, fatal neurodegenerative disorder characterized by the progressive loss of stri......
Genetic,epigenetic,and metabolic alterations are all hallmarks of cancer.However,the epigenome and metabolome are both h......
DNA methylation participates in regulating the expression of coding and non-coding regions in plants. To investigate the......
Asymmetric epigenome maps of subgenomes reveal imbalanced transcription and distinct evolutionary tr
The complexity of the epigenome landscape and transcriptional regulation is significantly increased during plant polyplo......
α-ketoglutarate promotes the specialization of primordial germ cell-like cells through regulating ep
There is growing evidence that cellular metabolism can directly participate in epigenetic dynamics and consequently modu......
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BACKGROUND:PTEN is well known to function as a tumor suppressor that antagonizes oncogenic signaling and maintains genom......
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为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
DNA methylation is a chemical modification of the bases in genomes. This modification, most frequently found at CpG dinu......
According to the developmental origin of health and disease concept,the risk of many age-related diseases is not only de......
α-ketoglutarate promotes the specialization of primordial germ cell-like cells through regulating ep
There is growing evidence that cellular metabolism can directly participate in epigenetic dynamics and consequently modu......
染色质开放性和染色质三维高级结构在基因表达和调控中发挥着非常重要的作用,广泛参与分化、发育、肿瘤发生等细胞生理过程,是表观......
成簇规律间隔短回文重复序列/成簇规律间隔短回文重复序列关联蛋白9（Clustered regularly interspaced short palindromic repeats/......
Are We Learning as Much as Possible from Spaceflight to Better Understand Health and Risks to Health
The objective of this review is to discuss the changes in human biology and physiology that occur when humans, who evolv......
AIM: To investigate epigenomic and gene expression alterations during cellular senescence induced by oncogenic Raf. METH......
Summary:Although the exact etiology of inflammatory bowel disease(IBD)remains unclear,exaggerated immune response in gen......
Cholangiocarcinoma(CCA)is a notoriously lethal epith-elial cancer originating from the biliary system.As radical resecti......
