rAAV相关论文
病毒工具的快速发展丰富了用于包括运动神经元疾病在内的多种临床疑难杂症的基因治疗手段。运动神经元疾病是一系列以上运动神经元......
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Neuronal tolerance to hypoxia-ischemia through recombinant adeno-associated viral vectors expressing
BACKGROUND:Studies have confirmed that neuronal nitric oxide synthase(nNOS)mediates neurotoxic effects during the early ......
目的研究重组腺相关病毒(recombinant adeno-associated virus,rAAV)介导的单纯疱疹病毒胸苷激酶(herpes simplex virus thymidine......
AAV-2是目前人类临床研究中最有前途的基因治疗载体之一。本论文报道了重组腺相关病毒rAAV-2的包装生产、纯化、检测方法即生产平......
Neuronal tolerance to hypoxia-ischemia through recombinant adeno-associated viral vectors expressing
BACKGROUND:Studies have confirmed that neuronal nitric oxide synthase(nNOS)mediates neurotoxic effects during the early ......
Suppressing tumor growth of nasopharyngeal carcinoma by hTERTC27 polypeptide delivered through adeno
Nasopharyngeal carcinoma(NPC) is a metastatic carcinoma that is highly prevalent in Southeast Asia. Our laboratory has p......
目的 探讨二种分别携带神经元型一氧化氮合酶(nNOS)、诱导型一氧化氮合酶(iNOS)反义RNA重组腺相关病毒载体(rAAV-AsnNOS和rAAV-Asi......
Suppressing tumor growth of nasopharyngeal carcinoma by hTERTC27 polypeptide delivered through adeno
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目的评价局部注射重组腺相关病毒介导胰岛素样生长因子-I（rAAV—IGF-I）对大鼠下颌髁突生长发育的影响。方法选用5周龄Sprague-Dawley......
目的评价局部注射重组腺相关病毒介导胰岛素样生长因子-I（rAAV—IGF-I）对大鼠下颌髁突生长发育的影响。方法选用5周龄Sprague-Dawley......
Effects of rAAV-CD151 and rAAV-antiCD151 on the Migration of Human Tongue Squamous Carcinoma Cell Li
This study was designed to determine the effects of the recombinant adeno-associated virus vector containing sense CD151......
重组腺相关病毒（r AAV）作为唯一一种通过欧盟FDA认证的基因治疗载体,具有宿主范围广、转染效率高、非致病性、免疫原性低、能够长期......
随着现代分子生物学的不断发展,以RNA干扰作用机制为指导原理的重组腺相关病毒成为了肿瘤基因治疗中最具研究潜力的载体,因此受到......
采用PCR和体外连接的方法构建了带有信号肽的脑源性神经营养因子（BDNF）的融合基因，将此基因插入到腺相关病毒载体穿梭质粒pSNAV,然后......
靶向性是肿瘤基因治疗取得成功的关键因素.在众多基因治疗病毒载体中,腺相关病毒(adeno-associatedvirus,AAV)是目前广为关注的基......
由于腺相关病毒(adeno-associated virus,AAV)的非致病性及能感染多种组织类型,重组AAV载体(rAAV)在基因治疗领域备受关注。然而,......
