suppressor相关论文
36. Study on p16INK4a and p15INK4b genes of human bronchial epithelial cells malignantly transformed
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The pre-mRNA processing factor Prp6 is an essential component of the U4/U6.U5 tri-small nuclear ribonucleoprotein (snRNP......
Mutation in PICKLE RELATED 2, an imprinted gene, suppresses seed abortion of thefertilization indepe
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The suppressors of sterol regulatory element binding proteins(SREBPs)in the regulation of lipid meta
Sterol regulatory element binding proteins(SREBPs)are members of membrane-bound,basic helix-loop-helix leucine zipper(bH......
Gender related long non-coding RNA FTX transcribed by X chromosome inhibits hepatocellular carcinoma
As long been known,males are more susceptible to hepatocellular carcinoma(HCC)than females,but the reason still remains ......
UvSMEKI,a Suppressor of MEK Null,Regulates Pathogenicity,Conidiation and Conidial Germination in Ric
Rice false smut,which is caused by Ustilaginoidea virens,is an emerging disease of rice spikelets in rice-growing areas ......
An oncolytic adenovirus delivering TSLC1 inhibits Wnt signaling pathway and tumor growth in SMMC-772
Tumor suppressor in lung cancer-1(TSLC1)was first identified as a tumor suppressor for lung cancer,and frequently downre......
UvSMEK1,a Suppressor of MEK Null,Regulates Pathogenicity,Conidiation and Conidial Germination in Ric
Rice false smut,which is caused by Ustilaginoidea virens,is an emerging disease of rice spikelets in rice-growing areas ......
Objective:To study the effects of antisense PTEN gene on the growth and invasion of glioma cells. Methods: A pcDNA3. 1/H......
HYPERMETHYLATION OF p14~(ARF) PROMOTER REGION AND EXPRESION OF p14~(ARF) GENE PRODUCT IN NON-SMALL C
Objective: This study was designed to investigate promoter methylation status and protein expression of p14ARF gene in n......
Comparison of gene expression profiles between primary tumor and metastatic lesions in gastric cance
AIM: To study the differential gene expression profiles of target cells in primary gastric cancer and its metastatic lym......
AIM:to analyze adipokine concentrations,insulin resistance and hepatic expression of suppressor of cytokine signaling 3(......
Expression and the role of myeloid-derived suppressor cells in the peripheral blood in patients with
Objective To investigate the correlation between the frequency of myeloid-derived suppressor cells(MDSC)and the frequenc......
Recently, suppressor of cytokine signaling-3(SOCS3) has been shown to be an inducible endogenous negative regulator of J......
瑞斯胆量矮子病毒(RGDV ) 是在中国和东南亚洲的重要米饭病原体。然而,很少对和植物房间的 RGDV 相互作用的分子的机制被知道。这里......
Aberrant methylation of Glutathione S-transferase P1 and E-cadherin in invasive ductal breast carcin
Objective To investigate the hypermethylation status of glutathione transferase P1(GSTP1)and E-cadherin(ECAD),TSGs(tumor......
HERBAL MEDICINE 960 RECIPE REGULATES THE PROLIFERATION AND APOPTOSIS OF HUMAN HEPATOMA CELL LINE SMM
To investigate the mechanism of 960 recipe regulating the proliferation and apoptosis of human hepatoma SMMC7721 cells.......
RNA silencing is a conserved mechanism found ubiquitously in eukaryotic organisms.It has been used to regulate gene expr......
Over the past years,it has been found that the epigenetic silence of tumor suppressor genes induced by overexpression of......
目的:检测髓源性抑制细胞(myeloid-derived suppressor cells,MDSCS)在人胃癌患者外周血及肿瘤组织中的分布比例,并分析其分布水平与胃......
Objective: To explore the loss of heterozygosity(LOH) on chromosome 6q in ovarian cancer, and localize a minimum area in......
Objective To study the percentage of peripheral blood CD4+ CD25+ T cells and the expression of F0XP3 mRNA in patients wi......
The tumor suppressor gene p53 regulates a wide range of cellular processes including cell cycle progression,proliferatio......
The highly conserved Notch signaling is precisely regulated at different steps in a series of developmental events. Howe......
Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. ......
CHROMOSOME 17P MAY HARBOR MULTIPLE TUMOR SUPPRESSOR GENES ASSOCIATED WITH PRIMARY GLIOBLASTOMA MULTI
Objective: To investigate whether deletion of chromosome 17 is involved in the carcinogenesis of primary glioblastoma mu......
Objective: To investigate the relationship between co-deletion of p15/p16 genes and the prognostic significance in patie......
CHROMOSOME 3 MAY HARBOR MULTIPLE TUMOR SUPPRESSOR GENES ASSOCIATED WITH PRIMARY GLIOBLASTOMA MULTIFO
Objective: To investigate whether deletion ofchromosome 3 is involved in the carcinogenesis of primary glioblastoma mult......
Role of genetic abnormalities of PTEN and the phosphatidylinositol 3kinase pathway in breast and ova
Breast and ovarian cancers exhibit several similar epidemiologic, genotypic and phenotypic characteristics suggesting th......
Objective: To investigate whether LCRG1 (Laryngeal Carcinoma Related Gene 1) has tumor suppressor function. Methods: The......
肝癌是一种发病率较高的恶性肿瘤,原发性肝癌的转移及其它恶性肿瘤的肝转移也较为常见。目前研究认为,某些基因的表达产物作用于......
Objective: To evaluate the effect of Cx43 gene on gap junction intercellular communication (GJIC) and proliferation of g......
PTEN was identified in 1997 as a new tumor suppressor gene on human chromosome 10q23, deletions and mutations of this ge......
To investigate genes involved in cancer metastasis, mRNA differential display was used to compare the levels of gene exp......
AIM:To refine the loss of heterozygosity on chromosome5p15 and to identify the new tumor suppressor gene (s) incolorect......
Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon
AIM:To investigate the effects of DNA methylation on theexpression of tumor suppressor genes and proto-oncogenein human......
The microcell mediated transfer of human chromosome 8 into highly metastatic rat liver cancer cell l
AIM Our previous research on the surgical samples ofprimary liver cancer with CGH showed that the loss of humanchromosom......
Mutation analysis of novel human liver-related putative tumor suppressor gene in hepatocellular carc
AIM:To find the point mutations meaningful for inactivationof liver-related putative tumor suppressor gene(LPTS)gene,a ......
AIM:To investigate gene expression pattern of human γ-synuclein gene in human esophageal squamous cellcarcinoma(ESCC)b......
AIM:To verify the effectiveness of denaturing high-performance liquid chromatography (DHPLC) in detectingsomatic mutati......
AIM:To investigate the effects of KAI1/CD82 on biologicalbehavior of colorectal carcinoma cells.METHODS:KAI1 cDNA was t......
Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutati
AIM:To investigate the relationship between Helicobacterpylori(H.pylori)infection and the expressions of the p53,Rb,c-m......
An early maturing maturing TGMS rice line 6442S-7 hascompletely dominant earliness mainly controlled by twodominant majo......
AIM: Loss of heterozygosity (LOH) on tumor suppressorgenes is believed to play a key role in carcinogenesis ofcolorecta......
Loss of heterozygosity on chromosome 10q22-10q23 and 22q 11.2-22q 12.1 and p53gene in primary hepato
AIM:To analyze loss of heterozygosity (LOH) and homozygousdeletion on p53 gene (exon2-3,4 and 11),chromosome10q22-10q23......
Genetic alterations and reduced expression of tumor suppressor p33~(ING1b) in human exocrine pancrea
AIM:To detect the expression of p33~(ING1b) protein and thechange of p33~(ING1b) gene in pancreatic carcinoma and toeva......
AIM:To analyze the genetic and epigenetic alterations ofRUNX3 gene,a potential putative tumor suppressor gene,in hepato......
Aim:To investigate the effect of 7-hydroxystaurosporine(UCN-01),a selectiveprotein kinase C(PKC)inhibitor,on cell growt......
AIM: Both development and progression of malignancies occur as a multistep process, requiring the activation of oncogene......
Hyaluronic acid induces osteopontin via the phosphatidylinositol 3-kinase/Akt pathway to enhance the
Hyaluronic acid (HA) binds to cell-surface receptors such as CD44, and seems to be involved in cell adhesion, motility, ......