toll-like相关论文
OBJECTIVE: To evaluate the efficacy of herb-partitioned moxibustion(HPM) at Qihai(CV6), Tianshu(ST25) and Shangjuxu(ST37......
Zhuifeng tougu capsules (追风透骨胶囊) improve rheumatoid arthritis symptoms in rats by regulating the tol
OBJECTIVE: To investigate the efficacy of Zhuifeng tougu capsules(追风透骨胶囊, ZFTG) in the treatment of rheumatoid art......
Comparative study on pattern recognition receptors in non-teleost ray-finned fishes and their evolut
Pattern recognition receptors(PRRs)play important roles in innate immunity system and trigger the specific pathogen reco......
目的探讨发热样温度对朗格汉斯细胞(Langerhans cells,LCs)表面抗原递呈相关分子CD40、CD80、CD86、HLA-DR以及Toll-like受体(Toll......
目的 探讨 Toll 样受体2(TLR2)及其信号通路下游因子在 HIV /结核分枝杆菌(M TB)双重感染者中的表达。方法选择 HIV 单纯感染者32例、H......
Toll样受体(TLRs)存在于细胞膜上,是一类跨膜受体.TLR4是TLRs家族中识别微生物和炎性反应的主要成员.肠道屏障主要包括机械、免疫......
目的:探讨实验性自身免疫性心肌炎BALB/c小鼠模型心肌组织中Toll样受体3的表达变化及意义。方法:用猪心肌肌球蛋白诱导建立BALB/c......
目的 探讨Toll样受体(TLRs)信号途径异常活化在急性EB病毒(EBV)感染免疫发病机制中的作用.方法 采用病例对照研究方法,选取急性EBV......
目的 观察乌司他丁对大鼠肝脏缺血-再灌注损伤以及缺血肝叶Toll样受体2(TLR2)表达的影响.方法 SD大鼠36只,随机分为假手术组、缺血......
Hepatitis B virus(HBV) infection is one of the major causes of liver diseases, affecting more than 350 million people wo......
目的研究屋尘螨(HDM)对于气道上皮Toll样受体4(TLR4)表达及T淋巴细胞分化的影响,以进一步探讨其在哮喘小鼠气道炎症中作用。方法雌性BA......
Hepatitis B virus induces expression of cholesterol metabolism-related genes via TLR2 in HepG2 cells
AIM:To investigate whether hepatitis B virus(HBV) exacerbates hepatic cholesterol accumulation,and explore the underlyin......
在许多发达国家中,约75%-80%的高血压患者有不同程度肥胖,65%-75%的原发性高血压患者同时合并有肥胖。随着社会的发展,中国的肥胖......
Toll-like receptors(TLRs) are a group of highly conserved molecules which initiate the innate immune response to pathoge......
Expression of Toll-like Receptor 4 in Neonatal Cord Blood Mononuclear Cells in Patients with Preecla
The expression of Toll-like receptor 4 (TLR4) in neonatal cord blood mononuclear cells (MNCs) and serum TNF-α were inve......
BACKGROUND: Methylprednisolone (MP) can affect the survival of CD4 + T lymphocytes and plays an important role in adapti......
目的探讨急性胆道梗阻时内毒素损伤小鼠肝脏的机制及其与TLR4表达的关系。方法雄性C57BL/10J(WT)小鼠42只,随机分为生理盐水组(NS组,n......
【正】 OBJECTIVE: To assess the effect of lipopolysaccharides (LPS) on the expression of CD14 and TLR4 inrat Kupffer cel......
【正】BACKGROUND: Toll-like receptor (TLR) 2/4 might play important roles in mediating proinflammatory cytokine synthesi......
BACKGROUND:Toll-like receptors (TLRs) are a family of type 1 transmembrane receptors, which can recognize different path......
BACKGROUND:Hepatitis B virus(HBV)is a hepatotropic, noncytopathic,DNA virus which can cause acute and chronic infection.......
BACKGROUND: Macrophages are widely-distributed innate immune cells playing diverse roles in various physiological and pa......
目的:观察长链游离脂肪酸对体外培养的角质形成细胞的作用,探讨其对TLR及NF—KB信号转导通路的影响。方法:①体外培养Hacat细胞,实验分......
试验旨在制备鼠抗鸡Toll样受体2(chTLR2)的多克隆抗体。采用RT-PCR方法从活化的鸡外周血淋巴细胞中扩增其胞外区片段chTLR2(chTLR2t1......
TLR-2(toll-like receptor 2,TLR-2)是哺乳动物TLRs(Toll-like receptors,TLRs)家族的一员,作为细胞表面的天然受体蛋白,主要参与病原......
目的克隆、表达人Toll-like receptor 2(TLR2)胞外段(A26-T588)基因,获得人TLR2胞外段蛋白.方法RT-PCR扩增TLR2胞外段基因,以pcDNA......
目的:研究吡格列酮对胰岛素抵抗(IR)自发性持续高血糖(OLETF)大鼠血清白细胞介素(IL)-18和Toll样受体4(TLR4)表达的影响及其降低心血管疾病......
利用RT-PCR、RACE及克隆等方法获得了异育银鲫Toll样受体3(cagTLR3)基因全长cDNA序列。该cDNA全长3170bp,5’端非编码区181bp;3’端非......
骨关节炎(osteoarthritis,OA)被认为是多因素疾病,目前有关其遗传因素的研究涉及了遗传方式及基因组的潜在突变位置等。最近的报道显示......
Abnormal innate immune responses toward luminal bacteria play an important role in the pathogenesis of inflammatory bowe......
Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis
AIM:To investigate the role of genetic polymorphisms in the progression of hepatic fibrosis in hereditary haemochromatos......
Hepatocellular carcinoma(HCC)is the most common form of liver cancer worldwide.It is caused by a variety of risk factors......
Toll-like receptors (TLRs) recognize specific motifs which are frequently present in bacteria, fungi, prokaryotes and vi......
Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alco
Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively kno......
Toll-like receptors(TLRs)are germ line encoded innate immune sensors that recognize conserved microbial structures and h......
AIM:To investigate inflammatory injury in the intestinal mucosa after intestinal ischemia-reperfusion(ⅡR) with Toll-lik......
Toll-like receptor 4 polymorphisms to determine acute pancreatitis susceptibility and severity: A me
AIM:To investigate the correlation of toll-like receptor 4(TLR4)gene Asp299Gly and Thr399Ile polymorphisms and acute pan......
AIM:To explore the effect of sophocarpine on experimental liver fibrosis and the potential mechanism involved.METHODS:So......
Effects of ω-3 fatty acids on toll-like receptor 4 and nuclear factor-κB p56 in lungs of rats with s
AIM To determine the effects of ω-3 fatty acids(ω-3FA) on the toll-like receptor 4(TLR4)/nuclear factor κB p56(NF-κB......
Faecal and mucosal microbiota in patients with functional gastrointestinal disorders: Correlation wi
AIM To investigate the intestinal luminal microbiota(LM)and mucosa-associated microbiota(MAM)in Chinese patients with fu......
AIM To evaluate the effect of oxymatrine(OMT) on hepatocyte apoptosis in rats with lipopolysaccharide(LPS)/D-galactosami......
目的:探讨实验性自身免疫性心肌炎BALB/c小鼠模型心肌组织中Toll样受体3的表达变化及意义。方法:用猪心肌肌球蛋白诱导建立BALB/c小......
目的:人类Toll样受体2(TLR2)是先天免疫系统中一个重要的病原微生物识别受体。本研究将建立广东汉族人群TLR2基因座位的功能性多态性......
目的:探讨脂多糖(LPS)对晶状体上皮细胞(LECs)Toll样受体4(TLR4)和CD14表达的影响。方法:采用不同浓度的LPS与体外培养的牛LECs共同孵育不......
目的:比较脐血与成人外周血粒细胞Toll样受体(TLRs)的表达情况,为新生儿相关疾病的临床治疗积累实验资料。方法:取脐血和成人外周血,用......
目的:检测HSP60及TLR4信号途径在小鼠心脏移植物中的表达情况,探讨其在心脏移植排斥反应中的作用以及它们之间的关系。方法:建立小鼠......
Objective: To explore the effects of transforming growth factor β1(TGF-β1) on dendritic cells (DC). Methods: Murine bo......