【摘 要】
:
From the first analysis of immuneprecipitation followed by Western blotting Corin and TLP seem to precipitate at the same height (approximately 50KDa) and are recognized by the same antibodies.Concurr
【机 构】
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Foundation De Beaumont Bonelli, Sbarro Health Research Organization, Temple University USA
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From the first analysis of immuneprecipitation followed by Western blotting Corin and TLP seem to precipitate at the same height (approximately 50KDa) and are recognized by the same antibodies.Concurrently we obtained a plasmid from Prof.Qingyu (Cleveland, Ohio) that let us transfect HEK293 cells and overexpress the human Corin with the purpose to evaluate by Western blotting (with anti-TLP and anti-Corin) whether the two proteins are really the same protein.In parallel we are improving the tests of immunoprecipitation by the use of cell extracts derived from lung cancer cells A549 and NCI-H23 with the aim to be able of obtaining a precipitate containing only the TLP.
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