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Aim Esophageal varix and portal hypertensive gastropathy (PHG) were complications of portal hypertension.Endoscopic esophageal varix eradication has been hypothetized to a trigger of PHGs aggravation.The aim of our study was to evaluate the effect of endoscopic variceal ligation (EVL) and endoscopic injection sclerotherapy (EIS) influencing on development of PHG.