Comparative protein-protein interaction analysis predicates distinct signature networks of metastati

来源 :第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 | 被引量 : 0次 | 上传用户:shijunjie88
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  Gene signatures of metastasis could be population specific.Precision cancer therapy focuses on ethnic groups and individual patients.Here we applied big datasets based comparative protein-protein interaction maps to screen the potential prognosis markers of metastasis and drug targets for Asian prostate cancer(PCa)patients.Genes that are overexpressed or underexpressed with at least two-fold change in metastatic PCa as compared to primary tumor were collected from twenty-five studies(microarray datasets).
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