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我院自1996年12月～1997年5月口服罗红霉素(Roxithromycin,罗力得)治疗下呼吸道感染64例。现将结果报道如下: 1 资料与方法 1.1 临床资料 64例均为成年住院患者,下呼吸道感染按解放军总后勤部卫生部编写的《临床疾病诊断依据、治愈、好转标准》确诊。男41例,女23例,年龄17～75岁,平均50.5岁。所有病例均有咳嗽、咳痰、肺部有干、湿性罗音,伴发热者21例。 1.2 方法 病源菌确定标准,以痰培养标本分离菌落比例占60％以上或口腔正常菌以外的细菌为致病菌,共分离出细菌67株,其中革兰氏阳性菌5种22株(32.8％),包括表皮葡萄球菌,金黄色葡萄球菌、肺炎球菌、链球菌、肠球菌、革兰氏阴性菌8种47株(67.2％),包括肺炎杆菌、克雷白杆菌、流感杆菌、沙雷杆菌、产碱杆菌,大肠杆菌、绿脓杆菌、变形杆菌等。
In our hospital from December 1996 to May 1997 oral roxithromycin (Roxithromycin) treatment of lower respiratory tract infection in 64 cases. The results are reported as follows: 1 Materials and Methods 1.1 Clinical data 64 cases are adult hospitalized patients, lower respiratory tract infection by the PLA General Logistics Department prepared by the Ministry of Health, “clinical diagnosis of disease, cure, improvement criteria” confirmed. 41 males and 23 females, aged 17 to 75 years, an average of 50.5 years old. All cases were cough, sputum, lungs have dry, wet rales, with fever in 21 cases. 1.2 methods to determine the source of pathogens to sputa culture specimens isolated colonies accounted for more than 60% of bacteria or oral normal bacteria as pathogens, a total of 67 bacteria were isolated, of which Gram-positive bacteria 5 22 (32.8% ), Including Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus, Enterococcus, Gram-negative bacteria in 47 species (67.2%), including Klebsiella pneumoniae, Klebsiella, influenza bacilli, Serratia , Alcaligenes, Escherichia coli, Pseudomonas aeruginosa, Proteus and so on.