【摘 要】
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Dear Editor,Homeostasis and repair are critical biological processes that allow for tissue and organ preservation and function in multi-cellular organisms.Their
【机 构】
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Gene Expression Laboratory, Salk Institute for Biological Studies,10010 North Torrey Pines Road, La
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Dear Editor,Homeostasis and repair are critical biological processes that allow for tissue and organ preservation and function in multi-cellular organisms.Their regulation and extension vary drastically across the animal kingdom,and mammals show limited tissue-specific regenerative capacity that declines with age.During aging,articular cartilage is one of the tissues that undergo substantial changes in the matrix structure,molecular composition,metabolic activity,and mechanical properties (Loeser et al.2016).
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