Cumulative pregnancy rates are useful when counselling couples about th eir cha nce of conceiving during infertility treatment. Especially in older patients who have a lower chance of conceiving cumulative pregnancy rates are important. Pat ients also have to be counselled about the physical and psychological stress of infertility treatment. In addition to the pregnancy rates, drop-out rates are a direct -and maybe themost important -marker of the physicians quality in an IVF program. Data of 394 in vitro fertilization (IVF) cycles in 151 patients ag ed ≥40 years were analysed retrospectively. Data were analysed using descriptiv e statistics as well as the Kaplan Meier procedure. A real cumulative pregnancy rate (RCPR) of 17.2%was achieved after 4 cycles with an expected cumulative pre gnancy rate (ECPR) of 35.4%. In patients aged 40-42 years a RCPR of 20.6%with an ECPR of 38.7%was reached, while the chances to conceive decreased rapidly a fter the age of 43 years (RCPR 12.1%). Adrop-out rate of non-pregnant patient s of 42.6-51.4%was observed after each cycle. Especially patients ≥40 years h ave to be counselled individually about their specific chances to conceive. The drop-out rate should be used as an important marker of quality control. Cumulative pregnancy rates are useful when counseling couples about th eir cha nce of conceiving during infertility treatment. Especially in older patients who have a lower chance of conceiving cumulative pregnancy rates are important. Pat ients also have to be counselled about the physical and psychological stress of In addition to the pregnancy rates, drop-out rates are a direct-and maybe themost important-marker of the physician’s quality in an IVF program. Data of 394 in vitro fertilization (IVF) cycles in 151 patients ag ed A real cumulative pregnancy rate (RCPR) of 17.2% was achieved after 4 cycles with an expected cumulative pre-gnancy rate (ECPR) of 35.4 %. In patients aged 40-42 years a RCPR of 20.6% with an ECPR of 38.7% was reached while the chances to conceive less rapidly a fter the age of 43 years (RCPR 12.1%). Ad rop-out rate of non-pregnant patient s of 42.6-51.4% was observed after each cycle. Especially patients ≥40 years h ave to be counselled individually about their specific chances to conceive. The drop-out rate should be used as an important marker of quality control.