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目的和方法：通过在体兔心肌缺血再灌注模型探讨缓激肽（ＢＫ） 对缺血再灌注心肌的延迟性保护。结果：ＢＫ 显著降低了２４ ｈ 后的心肌梗塞面积及血清肌酸磷酸激酶水平；多粘菌素Ｂ（ｐｏｌｙｍｙｘｉｎ Ｂ） － 蛋白激酶Ｃ 抑制剂，抑制了ＢＫ 的心肌保护作用。结论：ＢＫ 具有延迟性心肌保护作用，这一作用是通过ＰＫＣ 途径实现的
Objective and Methods: To investigate the delayed protection of bradykinin (BK) on myocardial ischemia-reperfusion in a rabbit model of myocardial ischemia-reperfusion. RESULTS: BK significantly reduced myocardial infarct size and serum creatine phosphokinase level after 24 h. Polymyxin B-protein kinase C inhibitor inhibited cardiomyocyte protective effect of BK. CONCLUSION: BK has a delayed cardioprotection that is mediated through the PKC pathway