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作者在2年半中观察到疑诊为伪膜性结肠炎患者39例,其中有组织学上诊断性特征者28例。此28例均接受了抗菌素治疗,22例发病于手术后,6例新近未接受手术。未接受手术的6例中2例死亡,均患有败血症且均于尸解时被偶然发现有伪膜性结肠炎,其余4例因感染在抗菌素治疗开始后6～10天出现腹泻,持续5～12天(平均8.2天),诊断均经乙状结肠镜检和活检确定。22例手术患者的腹泻或出现于抗菌素治疗之时,或出现于停用抗菌素后的10天之内,9例死亡,13例存活。9例死亡者除2例外,均系于尸解时方确诊为伪膜性结肠炎;存活的13例中,12例通过乙
In two and a half years, the authors observed 39 patients suspected of pseudomembranous colitis, of which 28 were histologically diagnosed. The 28 patients were treated with antibiotics, 22 patients after surgery, 6 patients have not undergone surgery. Two of the six patients who did not undergo surgery died of septicemia and were occasionally found to have pseudomembranous colitis at the time of autopsy. The remaining four had diarrhea 6 to 10 days after the start of the antibiotic treatment for 5 ~ 12 days (average 8.2 days), the diagnosis was confirmed by sigmoidoscopy and biopsy. The diarrhea of 22 surgical patients occurred either at the time of antibiotic treatment or within 10 days after antibiotic discontinuation, with 9 deaths and 13 surviving. Nine of the nine deaths were diagnosed as pseudomembranous colitis with the exception of two cases. Of the 13 survivors, 12 survived