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目的探讨硬化剂注射联合奥曲肽治疗食管静脉曲张破裂出血的临床效果。方法 108例食管静脉曲张破裂出血患者,按照随机数字表法分为研究组(给予硬化剂注射+奥曲肽治疗)与对照组(给予硬化剂注射治疗),各54例。治疗后随访15~20 d,对比分析两组患者的治疗效果。结果研究组患者止血时间短于对照组(P<0.05);研究组患者再出血发生率、针眼涌血发生率、不良反应发生率均低于对照组(P<0.05)。结论食管静脉曲张破裂出血患者采用硬化剂注射联合奥曲肽治疗,能取得较好的临床效果,值得进行深入研究和推广。
Objective To investigate the clinical effects of sclerotherapy combined with octreotide in the treatment of esophageal variceal bleeding. Methods A total of 108 patients with esophageal variceal bleeding were divided into study group (sclerotherapy + octreotide treatment) and control group (sclerotherapy injection) according to the random number table method, 54 cases in each group. After treatment, the patients were followed up for 15-20 days, and the therapeutic effects of the two groups were compared. Results The bleeding time of the study group was shorter than that of the control group (P <0.05). The incidence of rebleeding, the incidence of needle-hole bleeding and the incidence of adverse reactions in the study group were lower than those in the control group (P <0.05). Conclusion In patients with esophageal variceal bleeding using sclerotherapy injection combined with octreotide treatment, can achieve better clinical results, it is worth carrying out in-depth study and promotion.