儿童急性淋巴细胞白血病(ALL)的治愈是现代肿瘤化疗最突出的成就之一。大多数血液学家认为,小剂量6-巯基嘌呤(6-MP)和甲氨喋呤(MTX)的维持化疗对于治愈儿童ALL 是重要的。但是,有表明维持化疗确实有效的资料吗?如果维持化疗是有效的,那么它是怎样起作用的呢?维持化疗与预防复发:在强烈化疗之后,ALL 儿童接受6-MP 和MTX 维持化疗的效果尚未得到随机 The cure of childhood acute lymphoblastic leukemia (ALL) is one of the most prominent achievements of modern cancer chemotherapy. Most hematologists believe that maintenance chemotherapy with low doses of 6-mercaptopurine (6-MP) and methotrexate (MTX) is important for the cure of childhood ALL. However, are there any data that show that chemotherapy is really effective? If maintenance chemotherapy is effective, how does it work? Maintain chemotherapy and prevent relapse: Children with ALL receive 6-MP and MTX for chemotherapy after intense chemotherapy Effect has not been randomized