目的:探讨颅内原发性淋巴瘤的CT及MRI影像学特征及鉴别诊断。方法:对经立体定向活检病理证实的13例颅内原发性淋巴瘤的CT及MRI影像学表现进行了回顾性分析。结果:12例病灶发生于幕上,1例幕上、幕下均有发生。单发4例,多发9例;病灶为类圆形或不规则形,增强扫描病灶均可强化;对放、化疗敏感。结论:颅内原发性淋巴瘤CT及MRI表现有一定的特征性,综合CT及MR影像特点能够提高诊断准确率。 Objective: To investigate the CT and MRI features and differential diagnosis of intracranial primary lymphoma. Methods: The CT and MRI features of 13 cases of idiopathic intracerebral lymphoma proved by stereotactic biopsy were analyzed retrospectively. Results: Twelve lesions occurred on the screen, one in the screen and the other in the screen. Single in 4 cases, multiple in 9 cases; lesions were round or irregular shape, enhanced scan lesions can be enhanced; radiotherapy and chemotherapy sensitive. Conclusion: The manifestations of CT and MRI of intracranial primary lymphoma have certain characteristics. The characteristics of CT and MRI can improve the diagnostic accuracy.