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为探索中药治疗肝硬化,采用牛血清白蛋白(BSA)复制成大鼠肝纤维化模型,用图像分析仪定量观察鳖龙软肝片对模型大鼠肝纤维化的病理形态学改变,结果发现鳖龙软肝片有抑制大鼠肝脏胶原纤维合成作用。为该药的疗效机制及临床运用该药治疗肝纤维化、肝硬化提供依据。
In order to explore the treatment of liver cirrhosis by traditional Chinese medicine, bovine serum albumin (BSA) was used to replicate into liver fibrosis model in rats, and the pathomorphological changes of liver fibrosis in model rats were quantitatively observed with image analyzer. Qilong Ruangan Tablets inhibit the synthesis of collagen fibers in rat liver. For the drug efficacy mechanism and the clinical use of the drug for the treatment of liver fibrosis, cirrhosis provide the basis.