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目的探讨米非司酮联合甲氨蝶呤治疗子宫切口瘢痕妊娠的临床效果。方法选取子宫切口瘢痕妊娠患者74例,随机分为两组,对照组36例接受甲氨蝶呤治疗,观察组38例接受米非司酮联合甲氨蝶呤治疗,对比两组治疗效果与不良反应发生情况。结果观察组治疗总有效率为97.37%,显著高于对照组的72.22%;观察组不良反应发生率为13.1%,显著低于对照组的30.56%,差异均有统计学意义(P<0.05)。结论在子宫切口瘢痕妊娠治疗中,米非司酮联合甲氨蝶呤具有显著疗效,可有效改善患者的临床症状,提高生活质量,值得在临床中推广。
Objective To investigate the clinical effect of mifepristone combined with methotrexate in the treatment of uterine incision scar pregnancy. Methods Totally 74 patients with uterine incision scar pregnancy were randomly divided into two groups. 36 cases in the control group received methotrexate, 38 cases in the observation group received mifepristone combined with methotrexate. The curative effect and adverse effects of the two groups were compared Reaction occurred. Results The total effective rate in the observation group was 97.37%, significantly higher than that in the control group (72.22%). The incidence of adverse reactions in the observation group was 13.1%, which was significantly lower than that in the control group (30.56%, P <0.05) . Conclusion In the treatment of uterine incision scar pregnancy, mifepristone combined with methotrexate has a significant effect, which can effectively improve the clinical symptoms of patients and improve the quality of life, it is worth in the clinic.