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[目的]研究比较内镜黏膜下剥离术(ESD)与腹腔镜手术治疗早期胃癌的临床疗效。[方法]将行ESD治疗的早期胃癌患者28例作为治疗组,同期行腹腔镜手术治疗的早期胃癌患者28例作为对照组,比较2组患者的临床疗效。[结果]治疗组患者手术时间、术中出血量、住院时间、住院费用、并发症发生率分别为(55.2±19.5)min、(68.6±l1.2)ml、(6.5±2.1)d、(1.2±0.2)万元、7.14%,对照组患者分别为(75.3±17.9)min、(100.3±12.5)ml、(10.8±1.0)d、(5.1±0.3)万元、25.00%,2组比较差异均有统计学意义(P<0.05)。治疗组患者术后随访过程中有2例复发,均发生在术后3个月左右;对照组有1例复发,发生在术后5个月;2组复发率比较差异无统计学意义(P>0.05)。[结论]ESD与腹腔镜手术治疗早期胃癌的临床疗效相比,具有手术时间短、出血量少、创伤小、住院时间短、术后并发症少等诸多优势,安全有效,值得临床推广应用。
[Objective] To compare the clinical efficacy of endoscopic submucosal dissection (ESD) and laparoscopic surgery for early gastric cancer. [Methods] Twenty-eight patients with early gastric cancer who underwent ESD treatment were selected as the treatment group. Twenty-eight patients with early gastric cancer underwent laparoscopic surgery during the same period as the control group. The clinical efficacy was compared between the two groups. [Results] The operation time, intraoperative blood loss, hospitalization time, hospitalization expenses and complication rates in the treatment group were (55.2 ± 19.5) min, (68.6 ± 11.2) ml and (6.5 ± 2.1) d, respectively 1.2 ± 0.2) million and 7.14%, respectively. The patients in control group were (75.3 ± 17.9) min, (100.3 ± 12.5) ml, (10.8 ± 1.0) d and The differences were statistically significant (P <0.05). There were 2 cases of recurrence during the follow-up in the treatment group, all of which occurred in about 3 months after operation. One case of recurrence in the control group occurred at 5 months after operation. There was no significant difference in recurrence rate between the two groups (P > 0.05). [Conclusion] Compared with the clinical efficacy of laparoscopic surgery for early gastric cancer, ESD has the advantages of short operative time, less bleeding, less trauma, shorter hospital stay and fewer postoperative complications, which is safe and effective and worthy of clinical application.