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头颈外科 Haglund等报告了给7例青年期喉乳头状瘤病使用人白细胞干扰素的经验。用干扰素前肿瘤增长迅速,在干扰素治疗期间被抑制,治疗结束后又增长。如果把干扰素治疗作为消减瘤体的附加措施,可取得较好疗效。Burns等报告了对23例放射治疗失败后经受喉保守外科术的观察资料,16例保守外科术成功,然而4例由于癌存留和3例误吸,后来需全喉切除术。说明符合保守外科术标准的病人,在放疗后施行手术同未用过放疗的病人一样成功;但保守外科术有禁忌证的病人,如声带固定,则失败率高。在组织病理学-临床相互关系中,Johnson等发现被膜外癌播散(extracapsular spread,ECS)
Head and Neck Surgery Haglund et al. reported on the use of human leukocyte interferon in 7 cases of adolescent laryngeal papillomatosis. Tumor growth before interferon therapy was inhibited during interferon therapy and increased after treatment. If interferon therapy is used as an additional measure to reduce tumors, better results can be achieved. Burns et al. reported observational data of 23 patients who underwent laryngeal conservative surgery after failed radiotherapy. Sixteen conservative surgical procedures were successful. However, 4 patients had cancer retention and 3 aspirations and later required total laryngectomy. This shows that patients who meet the criteria of conservative surgery have the same success rate as patients who have not used radiation therapy after radiotherapy, but patients with contraindications to conservative surgery, such as vocal cord fixation, have high failure rates. In histopathology-clinical correlations, Johnson et al. found that extracapsular spread (ECS)