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红黄通脉冲剂(HHTM)灌胃给药,100mg·(kg.d)-1和200mg·(kg·d)-1(以其所含总黄酮量计算),连续7天。结果:均可明显延长小鼠的凝血时间和凝血酶原时间,抑制家兔的血栓形成和血小板的聚集率。
Honghuangtong pulsing agent (HHTM) was intragastrically administered, 100 mg·(kg.d)-1 and 200 mg·(kg·d)-1 (calculated based on total flavonoids contained therein) for 7 consecutive days. RESULTS: The clotting time and prothrombin time of mice were significantly prolonged, and the thrombosis and platelet aggregation rate of rabbits were inhibited.