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目的观察抚触配合单唾液酸四己糖神经节苷脂钠治疗新生儿缺氧缺血性脑病的临床效果。方法将新生儿缺氧缺血性脑病的患者256例,按照入院顺序分为试验组和对照组每组128例。对照组患者进行常规对症治疗,试验组患者在对照组的基础上使用单唾液酸四己糖神经节苷脂钠配合抚触,记录2组患者的疗效和3 d、12 d后的新生儿行为神经测定结果。结果经过治疗后,试验组总有效率为91.41%高于对照组的79.69%,患儿出生后3 d、12 d的行为神经测定评分均高于对照组,差异均有统计学意义(P<0.05)。结论抚触配合单唾液酸四己糖神经节苷脂钠治疗新生儿缺氧缺血性脑病具有良好的效果。
Objective To observe the clinical effect of combined administration of monosialotetrahexosyl ganglioside sodium on neonatal hypoxic-ischemic encephalopathy. Methods 256 neonates with hypoxic-ischemic encephalopathy were divided into two groups according to admission sequence: experimental group and control group, with 128 cases in each group. The patients in the control group were treated with conventional symptomatic treatment. The patients in the test group were treated with monosialotetrahexosyl ganglioside sodium on the basis of the control group. The curative effect of the two groups and the neonatal behavior after 3 and 12 days were recorded Nerve assay results. Results After treatment, the total effective rate in the experimental group was 91.41% higher than that in the control group (79.69%). The behavioral neurological scores at 3 and 12 days after birth in the experimental group were significantly higher than those in the control group (P < 0.05). Conclusion Touching with monosialotetrahexosyl ganglioside sodium treatment of neonatal hypoxic-ischemic encephalopathy has a good effect.