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约占全部恶性肿瘤1%的软组织肉瘤,由于术后易于局部复发及远处转移而致治疗失败,预后较差。近年来,随着对其生物学行为认识的深入及放疗技术的改进、新的化疗药物的问世等,综合治疗软组织肉瘤已趋定向,其预后大为改善。本文就软组织肉瘤手术治疗、放疗、化疗及综合治疗的现状予以综述。一、手术治疗由于软组织肉瘤可发生在机体任何部位,没有固定的解剖位置,故不可能有象乳腺癌、直肠癌等经典的根治术式。常用的术式有:(1)单纯肿瘤摘除术;(2)局部扩大切除术,(3)根治性局部切除术;(4)截肢
About 1% of all malignant tumors of soft tissue sarcoma, due to easy local recurrence and distant metastasis caused by treatment failure, the prognosis is poor. In recent years, with the deepening of its understanding of biological behaviors, the improvement of radiotherapy techniques, and the advent of new chemotherapeutic drugs, comprehensive treatment of soft tissue sarcoma has been oriented, and its prognosis has been greatly improved. This article reviews the current status of surgical treatment, radiotherapy, chemotherapy and comprehensive treatment of soft tissue sarcoma. First, the surgical treatment of soft tissue sarcoma can occur anywhere in the body, there is no fixed anatomical location, it is impossible to have a classic radical mastectomy surgery such as breast cancer, rectal cancer. The commonly used surgical methods are: (1) simple tumor resection; (2) local extended resection, (3) radical resection; (4) amputation