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应用本所研制的重组人粒细胞-巨噬细胞集落刺激因子（rhGM—CSF），按0．012和0．024mg／kg剂量静脉注射家犬可明显抗由环磷酰桉所致的白细胞减少和血小板减少；按0．075、0．15和0．3mg／kg剂量皮下注射经60Co照射致白细胞减少症的小且有明显恢复作用：增加脾细胞集落、外周血白细胞、骨髓有核细胞及巨噬细胞数。其药效强度与进口升白能近似。
Application of this study developed recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF), 0.012 and 0.024mg / kg dose of intravenous injection of dogs was significantly resistant to cyclophosphamide-induced leukopenia And thrombocytopenia; subcutaneous injection of 0.075,0.15 and 0.3mg / kg doses of 60Co irradiated leukopenia caused by small and significant recovery: increased splenocyte colonies, peripheral leukocytes, bone marrow cells and The number of macrophages. Its potency and import of white can be similar.