某些恶性肿瘤除其本身的特异性临床表现外,尚可发生其它一些与肿瘤有关的特殊的综合征这些综合征系肿瘤组织自身的异常代谢所导致的影响宿主全身的症候群,包括内分泌、神经肌肉系统、皮肤等一系列异常改变。Viallet等于1961年首先将这些症候群称为“肿瘤附生性综合征”(Paraneoplastic Synd-omes)。尔后20余年来,临床学家不但发现了更多的肿瘤附生性综合征的临床表现,而且对其发生机制进行了探讨。由于这些附生性综合征常可出现于肿瘤临床症状尚不明显时,因此,认识这些症候群将有助于 In addition to its own specific clinical manifestations of certain malignant tumors, there may be other special syndromes related to the tumor. These syndromes are caused by the abnormal metabolism of the tumor tissue itself and affect the symptoms of the host system, including endocrine and nerves. A series of abnormal changes such as muscle system and skin. Viallet et al. first described these syndromes as Paraneoplastic Synd-omes in 1961. Over the past 20 years, clinical scientists have not only discovered more clinical manifestations of tumor-associated syndromes, but also discussed the mechanism of its occurrence. Since these epidemiological syndromes can often occur when the tumor’s clinical symptoms are not yet obvious, understanding these syndromes will help