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一、肺癌化疗常用药物(一)细胞周期非特异性抗癌药物1.环磷酰胺(Cyclophosphamide,CPM)又名安道生(Endoxan,Cytoxan,CTX)是目前治疗肺癌最常使用的药物,抗肿瘤的选择性高、作用强、效果好。该药30%的活性部分由尿排出,故对膀胱有一定的刺激。近来主张大剂量冲击或中等量间歇用药,不主张小量每日给药。静脉注射,每次10～20mg/kg,1周1次或连用2～3天,疗程量为8～10g及成人可以1.0g/日,连用3～7日。目前,我院用法是:成人每次2.0g,间隔三周。国外最近有人采用每3周
1. Drugs commonly used for chemotherapy of lung cancer (I) Cell cycle non-specific anticancer drugs 1. Cyclophosphamide (CPM), also known as Endoxan (Cytoxan, CTX), is currently the most commonly used drug for the treatment of lung cancer. High selectivity, strong effect, good effect. 30% of the active part of the drug is excreted in the urine, so it has a certain degree of irritation to the bladder. Recently, high-dose shocks or moderate-dose intermittent medications have been advocated, and small daily doses are not advocated. Intravenous injection, each 10 ~ 20mg/kg, 1 week or once every 2 to 3 days, the amount of treatment is 8 ~ 10g and adults can be 1.0g / day, use 3 to 7 days. At present, the usage in our hospital is: every adult 2.0g, interval three weeks. Recently, foreigners have used every 3 weeks