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目的:探讨我院胆道手术患者抗菌药使用情况及其合理性。方法:2007年1月～2008年1月101例胆道手术患者抗菌药应用品种、用药例次、联合用药、药物利用指数进行统计分析。结果:101例手术全部通过静脉给予抗菌药,共涉及5大类23个品种211例次,使用频度最高的是:头孢菌素类(及加酶抑制剂)13种109例次,喹诺酮类4种51例次,共占总例次的75.9%。单用22例次,联用84例次,三联5例次。多数抗菌药DUI<1.0,术后停药时间平均为4.9d。结论:我院胆道切除术抗菌药使用存在一些不合理现象,需加强规范化管理。
Objective: To investigate the use of antibacterials in patients undergoing biliary tract surgery and its rationality. Methods: From January 2007 to January 2008, 101 cases of biliary tract surgery patients were investigated for antimicrobial application varieties, drug use times, combination therapy and drug utilization index. Results: All the 101 cases were given intravenous antibacterial drugs, involving 211 classes of 23 varieties in 5 major categories. The most frequently used ones were cephalosporins (plus enzyme inhibitors), 13 kinds of 109 cases, quinolones 4 kinds of 51 cases, accounting for 75.9% of the total cases. A single use of 22 cases, with 84 cases, triple triple cases. The majority of antibacterials DUI <1.0, the average postoperative withdrawal time was 4.9d. Conclusion: There are some unreasonable phenomena in the use of antimicrobial agents for biliary resection in our hospital, and the standardized management should be strengthened.