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目的 :探讨宫颈鳞癌年轻女性行宫颈癌手术治疗时同时行卵巢位移术(LOT)对患者的卵巢内分泌功能影响及并发症的发生情况。方法 :对本院妇科2011年7月~2013年7月收治的88年轻宫颈鳞癌妇女的临床及术后随访资料进行回顾性分析,根据是否进行LOT手术及接受术后放疗进行分层分析比较患者的激素水平及并发症的发生情况。结果 :术前LOT组和非LOT组的FSH、LH、E2、Kupperman评分值比较差异均不具有统计学意义;不放疗的患者,LOT和非LOT患者的卵巢功能指标(FSH、LH、E2、Kupperman评分)差异不显著,放疗的患者LOT组的卵巢功能指标(FSH、LH、E2、Kupperman评分)优于非LOT组;不放疗组的LOT组、非LOT组的卵巢功能指标(FSH、LH、E2、Kupperman评分)均优于放疗组的LOT组、非LOT组。对于LOT手术的患者,放疗患者的卵巢功能正常率72.73%与未放疗患者的96.67%差异不具有统计学意义;非LOT组患者中,放疗患者的卵巢功能减退率100%显著高于未放疗患者的5.56%。LOT手术的52例患者中,术后复查B超发现有1例患者盆腔积液,1例患者术后异位卵巢部位疼痛,非LOT组仅1例出现盆腔积液;两组术后并发症比较差异不显著。结论 :对于术后进行放疗治疗的患者,LOT手术可以有效对卵巢进行保护,但仍然受到射线的伤害。如果术后不进行放疗治疗,则患者的卵巢功能基本不受影响。
Objective: To investigate the effect of concurrent ovarian surgery (LOT) on ovarian endocrine function and the incidence of complications in cervical cancer patients undergoing cervical cancer surgery. Methods: The clinical and postoperative follow-up data of 88 women with cervical squamous cell carcinoma admitted to our hospital from July 2011 to July 2013 were retrospectively analyzed. The stratified analysis was made according to whether LOT surgery and postoperative radiotherapy were performed The patient’s hormone levels and the incidence of complications. Results: There was no significant difference in FSH, LH, E2 and Kupperman scores between preoperative LOT group and non-LOT group. In non-radiation group, the ovarian function indexes (FSH, LH, E2, Kupperman score), the ovarian function index (FSH, LH, E2, Kupperman score) in LOT group was better than non-LOT group in radiotherapy group; ovarian function index , E2, Kupperman score) were better than radiotherapy group LOT group, non-LOT group. For patients undergoing LOT surgery, the ovarian function normalization rate was 72.73% in radiotherapy patients and 96.67% in non-radiotherapy patients, but the non-LOT group was significantly lower than that in non-radiotherapy patients Of 5.56%. Of the 52 patients who underwent LOT, one patient had pelvic effusion after operation and one patient had postoperative ectopic ovarian pain. In the non-LOT group, only one patient had pelvic fluid. Postoperative complications The difference is not significant. CONCLUSIONS: LOT surgery is effective in protecting the ovaries of patients who have undergone radiotherapy, but is still subject to radiation damage. If not treated with radiotherapy, the patient’s ovarian function is basically unaffected.