论文部分内容阅读
目的:与经尿道前列腺等离子电切术(PKRP)进行对比研究,评估绿激光前列腺汽化术(PVP)治疗BPH的有效性和安全性。方法:2009年12月～2010年9月收治BPH患者70例,随机单盲分为两组,其中PVP组35例(研究组),PKRP组35例(对照组)。出院后3个月返院由专人负责复查,记录术前和出院后3个月的临床观察指标,包括国际前列腺症状评分(IPSS)、生活质量指数(QOL)、最大尿流率(Qmax)、男性性功能四项(MSF-4)以及并发症,采用SPSS13.0统计软件对上述资料进行统计学分析和评估。结果:两组患者术前指标、手术时间、术中冲洗液量、实验室检查、住院时间、导尿管拔除时间、膀胱冲洗时间差异无统计学意义(P>0.05)。出院后3个月,两组患者IPSS、QOL、Qmax均得到显著改善,MSF-4与术前相比差异无统计学意义。PVP组和PKRP组分别有2例(7.0%)和3例(10.0%)术后发生前尿道狭窄,发病率差异无统计学意义(P>0.05)。两组均未出现尿失禁。结论:PVP是一种治疗BPH的安全、有效的方法,短期(3个月内)疗效及安全性与PKRP类似,长期疗效有待随后进一步评估。
OBJECTIVE: To compare the efficacy of transurethral prostatectomy (PKRP) and evaluate the efficacy and safety of green laser prostatectomy (PVP) in the treatment of BPH. Methods: From December 2009 to September 2010, 70 patients with BPH were randomly divided into two groups, including 35 PVP patients (study group) and 35 PKRP patients (control group). The patients who returned to hospital 3 months after discharge were examined by hand and recorded the clinical observation indexes before and 3 months after discharge, including IPSS, QOL, Qmax, Male sexual function four (MSF-4) and complications, using SPSS13.0 statistical software for statistical analysis and evaluation of the above information. Results: There was no significant difference in preoperative indexes, operation time, intraoperative fluid volume, laboratory examination, hospitalization time, catheter removal time and bladder irrigation time between the two groups (P> 0.05). At 3 months after discharge, the IPSS, QOL and Qmax of both groups were significantly improved, while there was no significant difference between MSF-4 and preoperative. There were 2 cases (7.0%) and 3 cases (10.0%) of PVP group and PKRP group respectively. There was no significant difference in the incidence of urethral stricture between the two groups (P> 0.05). Urinary incontinence did not appear in either group. CONCLUSIONS: PVP is a safe and effective treatment for BPH. Short-term (within 3 months) efficacy and safety is similar to PKRP, and long-term efficacy needs to be assessed further.