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目的:探讨改良剥离式经尿道前列腺切除术(TUER-P)与经尿道前列腺切除术(TUR-P)治疗良性前列腺增生的疗效与安全性。方法:将111例具备手术指征的良性前列腺增生患者随机分为TUR-P组(63例)和改良TUER-P组(48例),记录比较两组手术时间、手术切除率、生活质量(QOL)评分、国际前列腺症状评分(IPSS)、最大尿流率(Qmax)以及术后逆向射精发生率。结果:改良TUER-P组手术时间短于TUR-P组,手术切除率高于TUR-P组,差异均有统计学意义(P<0.05)。术后3个月,两组IPSS、QOL评分及Qmax均较术前有显著改善,差异有统计学意义(P<0.05),但两组之间差异无统计学意义。改良TUER-P组术后逆向射精发生率低于TUR-P组术,差异有统计学意义(P<0.05)。结论:改良TUER-P术治疗良性前列腺增生具有手术时间短、手术切除率高、并发症少等优点,值得临床上推广应用。
Objective: To investigate the efficacy and safety of modified TURP-T and TUR-P in the treatment of benign prostatic hyperplasia. Methods: Totally 111 benign prostatic hyperplasia patients with surgical indications were randomly divided into TUR-P group (63 cases) and modified TUER-P group (48 cases). The operation time, surgical resection rate and quality of life QOL score, International Prostate Symptom Score (IPSS), maximum flow rate (Qmax), and incidence of postoperative adverse ejaculation. Results: The operative time of modified TUER-P group was shorter than that of TUR-P group, and the surgical resection rate was higher than that of TUR-P group. The difference was statistically significant (P <0.05). At 3 months after operation, IPSS, QOL score and Qmax in both groups were significantly improved compared with that before operation (P <0.05), but there was no significant difference between the two groups. The incidence of retrograde ejaculation in the modified TUER-P group was lower than that in the TUR-P group (P <0.05). Conclusion: Modified TUER-P in the treatment of benign prostatic hyperplasia has the advantages of short operative time, high surgical resection rate and few complications, which is worth popularizing and applying clinically.