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本文报告作者遇到的27例多原发恶性肿瘤,复习国内历年来有关报道,搜集多原发恶性肿瘤276例。根据这303例的情况,对国内多原发恶性肿瘤的特点进行了分析。与国外有关资料比较,国内多原发恶性肿瘤患者的年龄较轻,女性较多,主要侵犯消化系统和女性生殖系统。除成对器官、同一管道器官系统好发与国外报道相同外,还发现口、咽、耳、鼻、喉与食管、胃好组合发生多原发恶性肿瘤。此外,还对多原发恶性肿瘤的发病因素(特别是个体易感性)、近年来发病率升高的原因和研究多原发恶性肿瘤的意义进行了讨论。
In this article, the author reported 27 cases of multiple primary malignant tumors, reviewing domestic reports over the years, and collecting 276 cases of multiple primary malignancies. According to these 303 cases, the characteristics of multiple primary malignant tumors in China were analyzed. Compared with relevant data from abroad, patients with multiple primary malignant tumors in China are younger and more women, mainly invading the digestive system and the female reproductive system. Except that the paired organs and the same organ system were similar to foreign reports, it was found that multiple primary malignancies occurred in the mouth, pharynx, ear, nose, throat, esophagus, and stomach. In addition, the causes of multi-primary malignancy (especially individual susceptibility), the causes of increased incidence in recent years, and the significance of studying multiple primary malignancies have been discussed.