Objective:To explore the relationship between calcification of human vascular system and local inflammation using PET / CT. Methods:Patients who were treated with concurrent PET / CT in our hospital were collected continuously, and their arterial image data were analyzed in parallel with standardized uptake values. (SUV) and corresponding slice calcification score (CS) measurement. SUV values were collected and measured for slices with CS greater than 100. Patients were grouped according to CS, and the correlation analysis between SUV values and CS in each group was performed. Results:Overall CS and SUVmax (r = 0.62, P <0.05) and SUVmean (r = 0.59, P <0.05) were positively correlated, among which CS and SUV values were in the SUVmax (r = 0.72, P <0.05), SUVmean ( r = 0.59, P <0.05), SUVmax of CS 200-299 group (r = 0.71, P <0.05), SUVmean (r = 0.80, P <0.05), SUVmax of CS 300-399 group (r = 0.47, P <0.05 ), SUVmean (r = 0.53, P <0.05) were positively correlated, SUVmax (r =-0.17, P> 0.05), SUVmean (r =-0.07, P> 0.05) were negatively correlated in CS 400-499 group, CS There was no significant correlation between SUVmax (r = 0.22, P> 0.05) and SUVmean (r = 0.18, P> 0.05) in the 500 group. Conclusion:There is a certain correlation between the local vascular calcification area and the corresponding local inflammatory response in the calcification progress PET / CT has the potential to monitor early calcification.