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目的 探讨胃原发性恶性淋巴瘤的临床病理特点。方法 对 3 2例胃原发性非霍奇金恶性淋巴瘤的临床病理、免疫组化及超微结构进行观察。结果 3 2例恶性淋巴瘤原发于胃底 3例 ,胃体 7例 ,胃角 8例 ,胃窦14例。全部病例做免疫组化染色 ,证实B细胞性淋巴瘤 3 1例 (96 9% ) ,T细胞性淋巴瘤 1例 (3 1% )。另外 ,对11例非霍奇金恶性淋巴瘤和 6例胃未分化癌进行了对比电镜观察 ,发现二者的超微结构有明显的差异。结论 绝大多数胃原发性恶性淋巴瘤为B细胞来源 ;免疫组化和超微结构观察对本病的诊断和鉴别诊断具有十分重要的意义。
Objective To investigate the clinicopathological features of gastric primary malignant lymphoma. Methods The clinical pathology, immunohistochemistry and ultrastructure of 32 patients with gastric primary non-Hodgkin’s lymphoma were observed. Results 32 cases of malignant lymphoma were found in 3 cases of gastric fundus, 7 cases of gastric body, 8 cases of gastric corner and 14 cases of gastric antrum. Immunohistochemical staining in all cases confirmed 31 cases of B-cell lymphoma (96.9%) and 1 case of T-cell lymphoma (31%). In addition, 11 cases of non-Hodgkin’s lymphoma and 6 cases of gastric undifferentiated carcinoma were observed by electron microscopy and found that the ultrastructural differences between the two were obvious. Conclusions Most gastric primary malignant lymphomas are the source of B cells. Immunohistochemistry and ultrastructure observation are of great significance in the diagnosis and differential diagnosis of this disease.