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田七属活血化瘀类中药。本文进行动物实验(大 白鼠Walker256)及采用随机和双盲法临床观察鼻咽癌患者试验田七对放射治疗效果的影响。结果如下: 一、在50毫克/80~180克体重每天口饲一次,连续6天的剂量条件下,田七本身对Walker256动物肿瘤没有抑癌作用。 二、上述剂量的动物实验结果,鼻咽癌患者在放射治疗的全程口服田七(每次2克,每日3次,每周连续5天,总量180—240克)的临床观察,都表明田七可能具有增强电离辐射灭癌效应的作用。 三、田七在现用剂量下对放射治疗病人的肝、肾功能和免疫机能,以及血液有形成分方面,没有明显的不良效应。 四、临床两年随诊观察提示,要警惕田七可能有促进瘤细胞远处转移的倾向性。 五、生田七和熟田七在鼻咽癌患者放射治疗过程中,其效应大致相同。
Tian Qi is a traditional Chinese medicine for promoting blood circulation and removing blood stasis. In this paper, animal experiments (Walker 256) and the randomized and double-blind method were used to observe the effects of seven radiotherapy treatments in patients with nasopharyngeal carcinoma. The results are as follows: 1. In the condition of 50 mg/80-180 g body weight fed orally once a day for 6 consecutive days, Tian Qi itself has no tumor suppressing effect on Walker 256 animal tumors. Second, the above dose of animal experimental results, nasopharyngeal cancer patients in the whole course of radiation therapy Tianqi (2 grams each time, 3 times a day, 5 days a week, total 180-240 grams) clinical observations are It indicates that Tianqi may have the effect of enhancing the ionizing radiation and preventing cancer. 3. Tian Qi has no obvious adverse effects on the liver, kidney function and immune function of patients undergoing radiation therapy, and the formation of blood. Fourth, follow-up clinical observations for two years suggest that Tian Qi may be wary of promoting the distant metastasis of tumor cells. Five, Ikuta VII and cooked field VII in the course of radiation therapy in patients with nasopharyngeal carcinoma, the effect is roughly the same.