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就鳞状细胞癌抗原(SCCAg)作为肺部恶性肿瘤标记的敏感性和特异性,以及肿瘤分化、分期和肾衰竭对此的影响作用进行了研究.患者和方法:原发性胸部恶性肿瘤42例,其中鳞癌25例,小细胞癌10例,腺癌4例,间皮瘤2例,混合性鳞腺癌1例.良性呼吸系病变10例,健康受试者56人,肾衰竭17例.SCCAg测定采用放免药盒.结果:50名正常受试者SCCAg水平为0.4～2.6ng/ml,且95%<2.4ng/ml,故此值作为正常上限.11/25例鳞癌和1例混合型鳞
The sensitivity and specificity of squamous cell carcinoma antigen (SCCAg) as a marker of pulmonary malignancy, as well as the effects of tumor differentiation, staging, and renal failure were studied. Patients and Methods: Primary thoracic malignancy 42 Cases included 25 cases of squamous cell carcinoma, 10 cases of small cell carcinoma, 4 cases of adenocarcinoma, 2 cases of mesothelioma, 1 case of mixed squamous cell carcinoma, 10 cases of benign respiratory diseases, 56 cases of healthy subjects, and renal failure 17 Example: SCCAg assay using radioimmunoassay kits. Results: 50 normal subjects have SCCAg levels of 0.4 to 2.6 ng/ml and 95% <2.4 ng/ml, so this value is the upper limit of normal. 11/25 squamous cell carcinomas and 1 Mixed scale