Approximately half of the world' s population is at the risk of at least one vector-borne parasitic disease. The survival of intermediate hosts of vector-borne parasitic diseases is governed by various environmental factors, and remote sensing can be used to characterize and monitor environmental factors related to intermediate host breeding and reproduction, and become a powerful means to monitor the vector-borne parasitic diseases. Schistosomiasis is a parasitic disease that menaces human health. Oncomelaniahupensis ( snail) is the unique intermediate host of Schistosoma, so monitoring and controlling the number of snail is key to reduce the risk of schistosomiasis transmission. In this paper, Landsat 8 OLI and Sentinel 2 MSI data had been used to obtain the environmental factors ( vegetation, soil, temperature, terrain et al.), which are related to the multiplying and transmission of intermediate host. Then this study used T-S ( Takagi-Sugeno) Fuzzy RS model to establish a new suitable index membership function due to the different RS data, and a long time series monitoring of snail distribution in Dongting Lake from 2014 to 2018 was achieved. A comparative analysis was performed to validate the predicted results against the field survey data. The results demonstrated the accuracy of the developed model in predicting the distribution of snails.