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糖抗原50(CA-50)1982年Lindholm通过结肠-205结肠癌培养细胞,由免疫鼠获得,经单克隆抗体C-50识别的糖脂质。它存在于正常脏器如消化道、肝脏、胰腺和颌下腺等。这些脏器的肿瘤病人,血液中CA-50增加。据各家报告,其阳性率胰腺癌约为85%,胆道系统癌约为80%,结肠癌约为70%,慢性胰腺炎约有20%,作者的结果与上述结果大体相仿,以胰腺癌阳性率最高。胰腺癌CA-50的血液中浓度与CA19-9之间有较高的相关性,原因是两者的糖链结构类似,即CA19
Glycogen Antigen 50 (CA-50) Lindholm cultured cells through colon-205 colon cancer in 1982 and obtained from immunized mice, a lipid lipid recognized by monoclonal antibody C-50. It exists in normal organs such as digestive tract, liver, pancreas and submandibular glands. In patients with tumors of these organs, the blood CA-50 increased. According to reports, the positive rate of pancreatic cancer is about 85%, biliary system cancer is about 80%, colon cancer is about 70%, and chronic pancreatitis is about 20%. The author’s results are roughly similar to the above results, with pancreatic cancer. The highest positive rate. There is a high correlation between the blood concentration of pancreatic cancer CA-50 and CA19-9, because the sugar chain structure of both is similar, that is, CA19.