随着疾病的进展,多数T2DM患者最终需要接受胰岛素治疗。目前,得到广泛公认的药物治疗途径是由口服降糖药经过单一胰岛素逐渐过渡至多次、多种胰岛素注射治疗。无论是在胰岛素起始治疗中,还是在强化胰岛素治疗(基础胰岛素+餐时胰岛素方案)中,地特胰岛素的疗效都得到了证实,且相对于其他基础胰岛素而言,具有低血糖风险小、增重少、个体血糖更加稳定的优势。 As the disease progresses, most T2DM patients eventually need insulin treatment. At present, the widely recognized drug treatment approach is the gradual transition from oral hypoglycemic agents to single or multiple insulin injections, with multiple insulin injections. The efficacy of detemir has been demonstrated either in initial insulin therapy or in intensive insulin therapy (basal insulin + mealtime insulin regimen) and is associated with a lower risk of hypoglycemia relative to other basal insulins, Less weight gain, individual blood glucose more stable advantage.