MYELOID相关论文
靶向药物为急性髓系白血病(AML)治疗带来巨大进步。随着研究的深入,靶向药物治疗耐药、联合治疗不良反应叠加、缺乏有效靶点等问题亦......
目的:探究维奈克拉联合阿扎胞苷(Ven+AZA)在初治不适合强化疗(unfit)及难治(≥1次强化诱导化疗未缓解)/复发(R/R)急性髓系白血病(AML)患者中......
目的:探索开发一种靶向CLL-1的嵌合抗原受体T细胞(CAR-T细胞)并验证其功能。方法:通过流式细胞术检测急性髓系白血病(AML)细胞系和AML......
在酪氨酸激酶抑制剂(TKI)治疗时代,慢性粒细胞白血病(CML)已具有“慢病化管理”的趋势。虽然四代TKI药物相继出现,但是CML的治疗需求仍有......
目的:探讨长链非编码RNA(lncRNA)C9ORF139靶向微小RNA(miR)-24-3P/TAOK1调控急性髓系白血病(AML)细胞增殖的作用和机制。方法:AML细胞株(......
目的:探讨初诊急性髓系白血病(AML)患者的基因突变分布特点及其与预后的关系。方法:回顾性分析2016年5月至2019年12月就诊于空军军医......
目的:探讨低剂量地西他滨联合DA/HA化疗方案对预后中等及不良急性髓系白血病(AML)患者的疗效与安全性。方法:回顾性分析西南医科大学......
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IRF8 is a transcription factor with a critical role in B lymphocyte development and biological functions.In our previous......
E-26 Transformation-specific Related Gene Expression and Outcomes in Cytogenetically Normal Acute My
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目的探讨初始诱导失败急性髓系白血病(AML)患者应用米托蒽醌+环磷酰胺+阿糖胞苷(MAC)方案治疗的效果。方法抽取2018年5月至2021年5......
目的探讨初治急性髓系白血病(AML)患者诱导化疗后外周血淋巴细胞和单核细胞比值(LMR)在疗效评估及预后判断中的价值。方法回顾性分析山......
Chronic myeloid leukemia (CML) associated with pregnancy is a very rare situation (less than one case per 100</span></sp......
目的探讨维奈克拉在难治急性髓系白血病(AML)患者移植中的应用。方法回顾性分析2020年3月苏州大学附属第一医院收治的1例诱导治疗失......
当前复发难治急性髓系白血病(AML)的治疗仍然具有挑战性,复发难治AML患者还没有标准的治疗方法。目前研究认为参与涉及小分子靶向治疗......
Myeloid sarcoma of the colon as initial presentation in acute promyelocytic leukemia:A case report a
BACKGROUND Myeloid sarcoma(MS)rarely occurs in acute promyelocytic leukemia(APL)at onset,but it can develop in relapse c......
BACKGROUND Disseminated Fusarium is rare in healthy children.Children with hematological tumors may have secondary funga......
Secondary peripheral T-cell lymphoma and acute myeloid leukemia after Burkitt lymphoma treatment:A c
BACKGROUND Multiple primary cancer refers to more than one synchronous or sequential cancer in the same individual.Multi......
Risk factors of extramedullary relapse after allogeneic hematopoietic stem cell transplantation in p
Objective To evaluate risk factors and available treatments of extramedullary relapse (EMR) afterallogeneic hematopoieti......
Clinical characteristics,treatment pattern,and outcomes in newly diagnosed patients with chronic mye
Objective To explore the clinical characteristics,treatment patterns,and outcomes in newly diagnosed patients with chron......
Application of transcriptome sequencing and fusion genes analysis in the diagnosis of myeloid leukem
Objective To analyze the possible fusion genes with high-throughput transcriptome sequencing in myeloid leukemia patient......
Therapy-related myeloid leukemia during erlotinib treatment in a non-small cell lung cancer patient:
BACKGROUND Epidermal growth factor receptor tyrosine kinase inhibitors(EGFR-TKIs)are tolerable drugs used for patients w......
目的比较两种老年综合评估(CGA)方法(IACA和FIL-CGA)在评价老年急性髓系白血病(AML)患者预后中的价值。方法纳入97例2008年8月至2019年12......
目的评价基于二代测序(NGS)检测技术下的克隆性基因突变对核心结合因子相关急性髓系白血病(CBF-AML)预后的影响。方法回顾性分析2011年......
目的:探讨M-FISH技术在检测复杂核型中的价值。方法:联合应用常规细胞遗传学技术和M-FISH检测2例伴有复杂核型异常的急性髓细胞白......
Study of nucleophosmin (NPM) gene mutation in patients with acute myeloid leukemia and myelodysplast
Objective To investigate nucleophosmin (NPM) gene mutations in patients with de novo acute myeloid leukemia (AML) with n......
Grape seed proanthocyanidin extract induced mitochondria-associated apoptosis in human acute myeloid
The important aim in cancer treatment is the selective killing of cancer cells without damaging healthy cells and the mo......
Expression and the role of myeloid-derived suppressor cells in the peripheral blood in patients with
Objective To investigate the correlation between the frequency of myeloid-derived suppressor cells(MDSC)and the frequenc......
The solution-phase synthesis of a muramyl dipeptide(MDP) analogue of N~α-[4-chlorocinnamoyl-L-alanyl-D-isoglutaminyl]-L......
儿童慢性粒细胞性白血病(childhood chronic myeloid leukemia,CCML)是一种少见的儿童获得性造血干细胞恶性克隆增殖性疾病,仅占儿......
目的:检测髓源性抑制细胞(myeloid-derived suppressor cells,MDSCS)在人胃癌患者外周血及肿瘤组织中的分布比例,并分析其分布水平与胃......
目的探讨可溶性髓样细胞触发受体-1(soluble triggering receptor expressed on myeloid cells-1,sTREM-1)对脓毒血症的早期诊断价......
目的探讨不同程度肺挫伤患者外周血白细胞可溶性髓样细胞触发受体-1(soluble triggering receptor expressed on myeloid cell-1,s......
Relationship between Cytokines and Leukocytosis in Patients with APL Induced by All-Trans Retinoic A
Leukocytosis or hyperleukocytosis occurs during ATRA or arsenic trioxide differentiation therapy, which is related to th......
Effects of sulforaphane on Toll-like receptor 4/myeloid differentiation factor 88 pathway of monocyt
Objective To explore the effects of sulforaphane on Toll-like receptor 4(TLR4)/myeloid differentiation factor88(MyD88)pa......
Fetal rat models with neural tube defects were established by injection with retinoic acid at 10 days after conception. ......
Objective To study the effects of constantly slow intravenous arsenic trioxide (As_ 2 O_ 3 ) infusion regimen on decreas......
Application of a four antibody (cMPO/cCD79α/cCD3/CD45) combination to the diagnosis of acute leukemi
Objective To explore the diagnostic value of intracellular antibody combination in acute leukemia (AL) expressing cross-......
Glia Maturation Factor Gamma (GMFG): A Cytokine-Responsive Protein During Hematopoietic Lineage Deve
Human hematopoiesis was evaluated using the techniques of controlled stem cell differentiation, two-dimensional gel elec......
13.1 Erythrocyte and erythrocyte function2007388 Effect of Notch ligand Delta-1 on the differentiation and maturation o......
目的探讨急性白血病(acute leukemia,AL)免疫表型与预后的关系。方法采用流式细胞技术(FCM)对75例AL患者进行免疫表型分析,并评价......
急性髓性白血病(AML)是一种细胞内多基因突变导致造血祖细胞生长、增殖和分化异常的疾病。成年AML患者诊断时的核型是判断其愈后的......
Objective To explore the expression and clinical significance of Caudal-type homeobox transcription factor 2(CDX2) gene ......
Objective: JAK2 V617F, MPL W515L and JAK2 exon 12 mutations are novel acquired mutations that induce constitutive cytoki......
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EFFECTS OF IFN-a COMBINED WITH IL-6 ON GROWTH AND EXPRESSION OF THE GENES RELATED TO CELL-GROWTH AND
Objective:tTo investigate the effects of interferon-a (IFN-a) and IFN-a combined with interleukin-6 (IL-6) on growth and......
In recent years, there has been significant progress made in our understanding of the molecular genetics of myelodysplas......