PYRROLIDINE相关论文
Design,synthesis and preliminary biological evaluation of pyrrolidine derivatives as Mcl-1 inhibitor
The B-cell lymphoma(Bcl-2)family proteins are potential targets for cancer treatment.In our studies,a series of pyrrolid......
Chiral pyrrolidine-azole conjugates： Simple and efficient asymmetric organocatalysts for Michael add
简单 pyrrolidine-azole 结合被综合了并且发现了是为 nitrostyrenes 的不对称的迈克尔增加的有效催化剂。识别最佳的催化剂， pyrro......
Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides has been successfully......
Ring opening of aziridine with dialkyl amine took place readily in the presence of catalytic amounts of tri-n-butylphosp......
Synthesis and bioactivity of novel strobilurin derivatives containing the pyrrolidine-2,4-dione moie
(E)-Methyl-2-(2-(bromomethyl)phenyl)-3-methoxyacrylate was reacted with substituted 1-acetylpyrrolidine-2,4-diones and 3......
Synthesis and Crystal Structure of 1,7,8,9-Tetrachloro-4-benzyl-10,10-dimethoxy-4-azatricyclo(5,2,1,
The crystal structure of 1,7,8,9-tetrachloro-4-benzyl-10,10-dimethoxy-4-azatricyclo-(5,2,1,02,6)dec-8-ene-3,5-dione (C18......
报道了1条5HT_(2A)受体拮抗剂的高选择性合成路线.烯胺酰化/缩合一锅法可用于有效构建5,6,7,8-四氢吡啶[4,3-d]嘧啶核心结构,其中......
Thirteen thiomorpholine-bearing compounds were designed and synthesized as dipeptidyl peptidase IV(DPP-IV) inhibitors, w......
Synthesis of new type of Betti bases via three-component reaction of b-naphthol,cyclic amines and is
This work provided the first example of incorporating the oxindole moiety into the Betti bases.The new type of Betti bas......
A series of novel alkylthio/sulfinyl-8H-thieno[2,3-b]pyrrolizin-8-oximino derivatives V1―VIII15 were designed and synth......
An effcient formal synthesis of(+)-tashiromine was achieved by employing an intermolecular asymmetric Mannich-type react......
Three component reactions: An efficient and green synthesis of 3, 4-dihydropyrimidin-2-(1H)-ones and
An environmentally benign aqueous protocol for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones and thiones promoted by......
A novel bolaamphiphile surfactant N,N0-(octane-1,8-diyl)bis(pyrrolidine-2-carboxamide)(DAOP), was designed and synthesiz......
Photocrosslinkable Polynorbornene-based Block Copolymers with Enhanced Dielectric and Thermal Proper
Block copolymers poly(endo-N-3,5-bis(trifluoromethyl)biphenyl-norbornene-pyrrolidine)-block-poly(exo-N-(cinnamoyloxyethy......
Three pairs of novel 2-aryl-3,4,5-trihydroxypiperidines(6–8 and their enantiomers),the piperidine analogues of the pyrr......
1,3-Dipolar cycloaddition reaction for diastereoselective synthesis of functionalized dihydrospiro[i
The BF_3OEt_2 catalyzed one-pot 1,3-dipolar cycloaddition reaction of benzylamines,isatins and dimethyl acetylenedicarbo......
An improved and efficient method for synthesis of(lS,4S)-2-oxa-5-azabicyclo[2.2.1]heptane(1) from trans-4-hydroxy-L-prol......
A novel C-branched polyhydroxylated cyclic nitrone 25.which could be a valuable intermediate for the synthesis of C-bran......
Rocuronium bromide has been used as an aminosteroid non-depolarizing neuromuscular blocker and muscle relaxant.In this w......
Effects of antioxidants on homocysteine thiolactone-induced apoptosis in human umbilical vein endoth
Background and objectives Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Homocysteine th......
The phase of AlPO-21 was hydrothermally synthesized in the reactant system of diethylamine-RB-Al_2O_3-P_2O_5-H_2O-C_2H_5......
A highly efficient preparative procedure for ( R,S ) and ( S,S ) pyrrolidine 2 carboxylic acid 3,5 dioxa 4 ......
Synthesis of Chiral Aminophenols Based on Proline and Their Application in Enantioselective Addition
Three 2-{(3R,7As)-1,1-disubstituted-tetrahydro-1 H-pyrrolo[1,2-c][1,3]oxazol-3-yl}phenols have been synthesized fromsal......
The equilibrium geometries and UV visible spectra of a series of donor C 60 molecules were obtained by means of t......
Nucleophilic substitution reaction in polyfluoroaromaticsⅠ.Reactions with secondary amine nucleophil
Perfluorobenzene,chloropentafluorobenzene and dichlorotetrafluorobenzene werereacted with pyrrolidine,piperidine,morpho......
THE unique spherical nature and potential application of fullerene have attracted great attention. Their functionalizat......
A new class of chiral pyrrolidine ligands for homogeneous catalytic enantioselective cyclopropanatio
A new class of chiral pyrrolidine ligands have been successfully synthesized and their chiral induction abilities have ......
Theoretical Studies on Electronic Spectra and Second-order Nonlinear Optical Properties of N-methyl-
By using AM1 method, the structures and electronic properties of N-methyl-2-(2(-thiophene)-pyrrolo[3,4]C60 (MTPC) and N-......
A pyrrolidino[60]fullerene 1 with pyrrolidine group was synthesized and characterized. The UV-Vis spectra showed that th......
substituted hexahydro-1H-1,4-diazepine analogues were synthesized starting from N,N?-dibenzyl-1,3-propylene diamine and ......
S-(-)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2,3-dimethoxybenzamide (proposed generic name, epidepride) is a very pot......
N-Boc-2, 5-bis(trimethylsilyl)pyrrolidine 4 was synthesized from the reaction of N-Boc-pyrrolidine 1 with trimethylsilyl......
AIM: To evaluate whether pyrrolidine dithiocarbamate (PDTC), an enhancer of HO production, attenuates intestinal IR inju......
Nuclear factor-kappaB activation on the reactive oxygen species in acute necrotizing pancreatitic ra
AIM: To investigate the potential role of nuclear factor kappa-B (NF-KB) activation on the reactive oxygen species in ra......
AIM: To explore the changes of nuclear factor-kappa B (NF-κB) DNA-binding activity, the expression of intercellular adh......
Evaluation of the effect of pyrrolidine dithiocarbamate in suppressing inflammation in mice with dex
AIM: To evaluate the effect of pyrrolidine dithio- carbamate (PDTC; an NF-κB inhibitor) administered at low (50 mg/kg) ......
Helicobacter pylori tumor necrosis factor-α inducing protein promotes cytokine expression via nuclea
阜阳市局 ￡4a 局长——_MINtkMMtgj’＃lnH＄B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
Pyrrolidine dithiocarbamate alleviates the anti-tuberculosis drug-induced liver injury through JAK2/
Objective:To study the effect of pyrrolidine dithiocarbamate(PDTC) on the anti-tuberculosis drug-induced liver injury an......
Hydrogen sulfide attenuates gastric mucosal injury induced by restraint water-immersion stress via a
AIM To explore the effect of hydrogen sulfide(H2S)on restraint water-immersion stress(RWIS)-induced gastric lesions in r......
烟酸为吡啶(pyridine)衍生物,其化学名为3-吡啶甲酸(pyridine-3-carboxylic acid)。其制备方法很多,今就我厂试制经验介绍于下,以......
期刊
古豆碱(hygrine)是一种存在于许多植物如曼陀罗、莨菪、烟草和古柯中的生物碱。最近,发现该吡咯烷(pyrrolidine)生物碱是莨菪烷(t......
胡椒科植物 P.hispidum H.B.K.叶的二氯甲烷提取物对分枝孢子菌属真菌球孢枝孢 Cladosporium sphaerospermum 有抑制活性(MIC=109......
Bepridil盐酸盐{β-[(2-methyl-propoxy)-methyl]-N-Phenyl-N-(phenylmethyl)-l-pyrrolidine-ethanaminc monohydrochloride mono......
Lipid-associated membrane proteins of Mycoplasma penetrans induce production of proinflammatory cyto
The aim of this study is to explore potential pathogenicity of Mycoplasma penetrans, and to investigate whether M.penetr......
A new 4-methoxyphenyl substituted C60-pyrrolidine derivative, C60(C10H13NO) (1), was prepared and its room-temperature ......
Reaction of C60 with DL-valine and cyclohexanone in refluxing chlorobenzene under N2 yields three [60]fulleropyrrolidin......
N-AcetyI-L-cysteine and pyrrolidine dithiocarbamate inhibited nuclear factor-κB activation in alveol
Aim:To study the effects of N-acetyl-L-cysteine(NAC)and pyrrolidine dithio-carbamate(PDTC)on the phosphorylation of Iκ......
(+)-Preussin (1) and its 5-epimer were synthesized from the divmylcarbmol (3) with Sharpless asymmetric epoxidation of ......
The computations of the electronic structures and properties of a novel crowned [60] fulleropyrrolidine (CFP) were perf......
