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  5. Pharmacokinetic comparisons of Yu Ping Fang San with the different combinations of its constituent h

Pharmacokinetic comparisons of Yu Ping Fang San with the different combinations of its constituent h

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：viagra2
【摘 要】
：
Aim: Yu Ping Fang San (YPFS) is a well-known traditional Chinese medicine formula, containing Radix Saposhnikoviae (RS), Radix Astragali (RA) and Rhizoma Atractylodis Macrocephalae (RAM).Cycloastragen
【作 者】
：
Tao LI Yi-wei WANG Yan-li WANG Ri-xin LIANG Dong ZHANG Hui-hui ZHANG Li CHEN Zhong-ming ZHOU Wei-peng YANG 
【机 构】
：
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, Chin
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
Yu Ping Feng San pharmacokinetics cycloastrageno cimifugin herbal combination 
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Aim: Yu Ping Fang San (YPFS) is a well-known traditional Chinese medicine formula, containing Radix Saposhnikoviae (RS), Radix Astragali (RA) and Rhizoma Atractylodis Macrocephalae (RAM).Cycloastragenol and cimifugin are the key metabolites, which show good pharmacokinetic properties in vivo and simultaneously possess strong biological activities relevant to the effects of YPFS.The aim of this study is to compare the pharmacokinetics of cycloastragenol and cimifugin in rat plasma after oral administration of YPFS with differentcombinations of its constituent herbs.
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