The analgesic and anticancer effects of minimally toxic fraction from Liu-shen-Wan and the underlyin

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户:chester116
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aim: Liu-Shen-Wan (LSW), an ancient preparation used to treat localized infection with pain, was reported to possess anticancer activity.We obtained a LSW supernatant (LSWS) fraction from ultrasound-assisted ethanol extraction (yield 15.9%) which proved to be safer than LSW in terms of hepatotoxicity.
其他文献
Aim: 5 Adenosine monophosphate-activated protein kinase (AMPK) was reported to form transcriptional complex with peroxisome proliferator-activated receptor delta (PPARδ) to induce gene expression syne
Aim: Hyperlipidaemia, a prevalent disease, is a high risk factor of cardiovascular disease.However, effective and safe pharmacological option for its treatment remains limitation.In order to acquire m
Aim: Failure to engage apoptosis appears to be a leading mechanism of resistance to traditional platinum drugs in patients with ovarian cancer.Therefore, an alternative strategy to induce cell death i
Aim: Cucurbitacin B (Cuc B), a natural triterpenoid with potent anti-cancer activities both in vitro and in vive, induces cancer cells cycle arrest at S or G2/M phases while the detailed mechanisms re
Aim: To investigate the effects of Compound Astragalus and Salvia Miltiorrhiza Extract (CASE) on cell migration of keloid fibroblasts (KFs) and its mechanisms involving mitogen-activated protein kinas
Aim: The treatment failure of methicillin resistant Staphylococcus aureus (MRSA) infections and emergence of vancomycin-resistant Staphylococcus aureus (S aureus) urgently requires developing new anti
Aim: β3-Adrenergic receptor (β3-AR) gene is associated with insulin resistance and may affect serum uric acid levels.Our aim was to determine the possible association between β3-AR gene Trp64Arg polym
Aim: Amyloid beta (Aβ)-induced synaptic dysfunction is thought to be an important event in early stage of Alzheimers disease (AD).In this study, the effect of NR2B antagonist against Aβ25-35 induced a
Stroke is a major health problem throughout the world.The elevated blood pressure (BP) after stroke is a common complication associated with poor outcome and is less understood.Since the crucial role
Aim: Bone morphogenetic protein type Ⅱ receptor (BMPR-Ⅱ) mutations are responsible for over 70% of cases of heritable pulmonary arterial hypertension (PAH) and up to 15%-40% of sporadic idiopathic dis