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目的探讨阿托品对房颤冷冻消融患者术中及术后血管迷走反射的预防作用。方法回顾性分析2016年1月至2017年1月在我院行经皮心脏冷冻消融术患者240例的临床资料,根据术中有无应用阿托品分为阿托品组(n=153)和非阿托品组(n=87),比较两组迷走反射发生率。结果阿托品组发生血管迷走反射3例(发生率2%),非阿托品组发生10例(发生率11.4%)。两组迷走反射的发生率差异有显著性(χ~2=9.839,P<0.05)。结论术中静脉应用阿托品对迷走反射发生有明显的预防作用,能有效减少术中及术后血管迷走反射发生率。
Objective To investigate the preventive effect of atropine on intraoperative and postoperative vasovagal reflex in patients with atrial fibrillation undergoing cryoablation. Methods The clinical data of 240 patients who underwent percutaneous cardiac cryosurgery in our hospital from January 2016 to January 2017 were retrospectively analyzed. According to the presence or absence of atropine, the patients were divided into atropine group (n = 153) and non-atropine group n = 87). The incidence of vagal reflex in both groups was compared. Results In the atropine group, vasovagal reflex occurred in 3 cases (2% incidence) and in the non-atropine group (10 cases) (incidence 11.4%). There was a significant difference in the incidence of vagal reflex between the two groups (χ ~ 2 = 9.839, P <0.05). Conclusion Intraoperative intravenous atropine has a significant preventive effect on vagal reflex, which can effectively reduce the incidence of intraoperative and postoperative vascular vagal reflex.